@article{fdi:010083784, title = {{A} community-based healthcare package combining testing and prevention tools, including pre-exposure prophylaxis ({P}r{EP}), immediate {HIV} treatment, management of hepatitis {B} virus, and sexual and reproductive health ({SRH}), targeting female sex workers ({FSW}s) in {C}ote d'{I}voire : the {ANRS} 12381 {PRINCESSE} project}, author = {{B}ecquet, {V}alentine and {N}ouaman, {M}. and {P}lazy, {M}. and {A}goua, {A}. and {Z}ebago, {C}. and {D}ao, {H}. and {M}ontoyo, {A}. and {J}ary, {A}. and {C}offie, {P}. {A}. and {E}holie, {S}. and {L}armarange, {J}oseph and {ANRS} {PRINCESSE} {T}eam,}, editor = {}, language = {{ENG}}, abstract = {{B}ackground: {P}re-exposure prophylaxis ({P}r{EP}) is recommended by the {WHO} for {HIV} prevention among female sex workers ({FSW}s). {A} study conducted in 2016-2017 in {C}ote d'{I}voire showed that if {P}r{EP} is acceptable, {FSW}s also have many uncovered sexual health needs. {B}ased on this evidence, the {ANRS} 12381 {PRINCESSE} project was developed in collaboration with a community-based organization. {T}he main objective is to develop, document, and analyze a comprehensive sexual and reproductive healthcare package among {FSW}s in {C}ote d'{I}voire. {M}ethods: {PRINCESSE} is an open, single-arm interventional cohort of 500 {FSW}s in {S}an {P}edro ({C}ote d'{I}voire) and its surroundings. {R}ecruitment started on {N}ovember 26th, 2019 and is ongoing; the cohort is planned to last at least 30 months. {T}he healthcare package (including {HIV}, hepatitis {B}, and sexually transmitted infection management, pregnancy screening, and contraception) is available both at mobile clinics organized for a quarterly follow-up (10 intervention sites, each site being visited every two weeks) and at a fixed clinic. {F}our waves of data collection were implemented: (i) clinical and safety data; (ii) socio-behavioral questionnaires; (iii) biological data; and (iv) in-depth interviews with female participants. {F}our additional waves of data collection are scheduled outside the cohort itself: (i) the medical and activity records of {A}prosam for the {PRINCESSE} participants; (ii) the medical records of {HIV}+ {FSW} patients not participating in the {PRINCESSE} cohort, and routinely examined by {A}prosam; (iii) in-depth interviews with key informants in the {FSW} community; and (iv) in-depth interviews with {PRINCESSE} follow-up actors. {D}iscussion: {T}he {PRINCESSE} project is one of the first interventions offering {HIV} oral {P}r{EP} as part of a more global sexual healthcare package targeting both {HIV}- and {HIV}+ women. {S}econd, {STI}s and viral hepatitis {B} care were offered to all participants, regardless of their willingness to use {P}r{EP}. {A}nother innovation is the implementation of mobile clinics for chronic/quarterly care. {I}n terms of research, {PRINCESSE} is a comprehensive, interdisciplinary project combining clinical, biological, epidemiological, and social specific objectives and outcomes to document the operational challenges of a multidisease program in real-life conditions.}, keywords = {{HIV} prevention ; {S}exual and reproductive health ; {S}exually transmitted ; infections ({STI}s) ; hepatitis {B} ; {P}re-exposure prophylaxis ({P}r{EP}) ; {S}ex work ; {M}ixed-methods research ; {M}obile clinics ; {C}ote d'{I}voire ; {COTE} {D}'{IVOIRE}}, booktitle = {}, journal = {{BMC} {P}ublic {H}ealth}, volume = {21}, numero = {1}, pages = {2214 [14 p.]}, year = {2021}, DOI = {10.1186/s12889-021-12235-0}, URL = {https://www.documentation.ird.fr/hor/fdi:010083784}, }