@article{fdi:010083642,
  title = {{E}valuation of indoxacarb, an oxadiazine insecticide for the control of pyrethroid-resistant {A}nopheles gambiae ({D}iptera : {C}ulicidae)},
  author = {{N}'{G}uessan, {R} and {C}orbel, {V}incent and {B}onnet, {J}ulien and {Y}ates, {A}. and {A}sidi, {A}. and {B}oko, {P}. and {O}djo, {A}. and {A}kogbeto, {M}. and {R}owland, {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{O}wing to the spread of pyrethroid resistance in {A}nopheles garnbiae s.s. ({D}iptera: {C}ulicidae) and other vector mosquitoes, there is an urgent need to develop alternative insecticides to supplement the pyrethroids for malaria control. {I}ndoxacarb is an oxadiazine insecticide initially commercialized by {D}u{P}ont for control of agricultural pests. {P}erformance against {A}n. gambiae bearing kdr (pyretbroid and {DDT} resistance) or {A}ce-1({R}) insensitive acetylcholinesterase (organ ophospbate and carbamate resistance) mechanisms was studied using larval and adult bioassays and a simulated experimental hut system (tunnel tests) that allows fuller expression of the behavioral responses to insecticide. {L}arval and adult bioassays (topical application and cone tests on treated netting) showed a standard probit dosage-mortality response and no evidence of cross-resistance to the kdr and {A}ce-1({R}) resistance mechanisms. {T}oxic activity was slow compared with standard insecticides and additional mortality was observed. {I}ndoxacarb induced no excitorepellency in adults. {I}n tunnel tests, indoxacarb induced no inhibition of mosquito penetration or blood feeding through the holed netting, but it induced delayed mortality over 24-96 h. {T}here was > 90% mortality of the kdr strain on netting treated with the 500 mg/m(2) dosage, whereas permethin at 500 mg/m(2) only killed 30% of this strain. {A} mixture of indoxacarb and pyretbroid showed neither synergism nor antagonism. {T}he absence of cross-resistance to current insecticides indicates that indoxacarb lias malaria vector control potential as larvicide or adulticide where mosquitoes are pyretbroid resistant.},
  keywords = {indoxacarb ; mosquito ; {A}nopheles gambiae ; insecticide resistance},
  booktitle = {},
  journal = {{J}ournal of {M}edical {E}ntomology},
  volume = {44},
  numero = {2},
  pages = {270--276},
  ISSN = {0022-2585},
  year = {2007},
  DOI = {10.1603/0022-2585(2007)44[270:eoiaoi]2.0.co;2},
  URL = {https://www.documentation.ird.fr/hor/fdi:010083642},
}