@article{fdi:010083353,
  title = {{I}nsecticide resistance profiles in malaria vector populations from {S}ud-{K}ivu in the {D}emocratic {R}epublic of the {C}ongo},
  author = {{N}'{D}o, {S}. and {B}andibabone, {J}. {B}. and {S}oma, {D}. {D}. and {M}usaka, {B}. {Z}. and {P}rudhomme, {J}. and {H}abamungu, {C}. {C}. and {N}amountougou, {M}. and {S}angare, {I}. and {K}ientega, {M}. and {K}abore, {D}. {A}. {P}. and {B}ayili, {K}. and {Y}erbanga, {R}. {S}. and {D}iabate, {A}. and {D}abire, {R}. {K}. and {O}uedraogo, {J}. {B}. and {B}elem, {A}. {M}. {G}. and {B}o{\¨e}te, {C}hristophe and {G}uardiola-{C}laramonte, {M}. and {C}himanuka, {B}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {I}nsecticide resistance has become a widespread problem causing a decline in the effectiveness of vector control took in sub-{S}aharan {A}frica. {I}n this situation, ongoing monitoring of vector susceptibility to insecticides is encouraged by the {WHO} to guide national malaria control programmes. {O}ur study was conducted from {A}pril to {N}ovember 2018 in {T}chonka ({S}ud-{K}ivu, {D}emocratic {R}epublic of the {C}ongo) and reported primary data on the resistance status of {A}nopheles funestus and {A}nopheles gambiae. {M}ethods: {I}nsecticide susceptibility bioassays were performed on wild populations of {A}. funestus and {A}. gambiae using {WHO} insecticide-impregnated papers at discriminating concentration. {I}n addition, {PCR} was performed to identify mosquito species and to detect kdr and ace-1({R}) mutations involved in insecticide resistance. {R}esults: {B}ioassay results show resistance to all tested insecticides except pirimiphos-methyl, propoxur, fenitrothion and malathion with a mortality rate ranging from 95.48 to 99.86%. {T}he addition of piperonyl butoxide ({PBO}) increased the susceptibility of vectors to deltamethrin and alpha-cypermethrin by exhibiting a mortality ranging from 91.50 to 95.86%. {T}he kdr mutation was detected at high frequencies (approximately 0.98) within {A}. gambiae while ace-1({R}) was not detected. {C}onclusions: {T}his study provides useful data on the insecticide resistance profiles of malaria vector populations to better manage vector control. {O}ur results highlight that, despite the high level of resistance, organophosphorus compounds and pyrethroids + {PBO} remain effective against the vectors.},
  keywords = {{A}nopheles funestus ; {A}nopheles gambiae ; {D}emocratic {R}epublic of the {C}ongo ; insecticide resistance ; {M}alaria ; {REPUBLIQUE} {DEMOCRATIQUE} {DU} {CONGO} ; {SUD} {KIVU}},
  booktitle = {},
  journal = {{T}ransactions of the {R}oyal {S}ociety of {T}ropical {M}edicine and {H}ygiene},
  volume = {115},
  numero = {11},
  pages = {1339--1344},
  ISSN = {0035-9203},
  year = {2021},
  DOI = {10.1093/trstmh/trab116},
  URL = {https://www.documentation.ird.fr/hor/fdi:010083353},
}