Horizon 1 1 17 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES Veterinary Medicine and Science 14-20 cats mild-respiratory clinical signs NGS One Health SARS-CoV-2 serology FRANCE 2022 fdi:010083280 ENG Veterinary Medicine and Science ISI:000711265700001 1 10.1002/vms3.638 https://www.documentation.ird.fr/hor/fdi:010083280 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/2021-12/010083280.pdf 8 Horizon (IRD) Although there are several reports in the literature of SARS-CoV-2 infection in cats, few SARS-CoV-2 sequences from infected cats have been published. In this study, SARS-CoV-2 infection was evaluated in two cats by clinical observation, molecular biology (qPCR and NGS), and serology (microsphere immunoassay and seroneutralization). Following the observation of symptomatic SARS-CoV-2 infection in two cats, infection status was confirmed by RT-qPCR and, in one cat, serological analysis for antibodies against N-protein and S-protein, as well as neutralizing antibodies. Comparative analysis of five SARS-CoV-2 sequence fragments obtained from one of the cats showed that this infection was not with one of the three recently emerged variants of SARS-CoV-2. This study provides additional information on the clinical, molecular, and serological aspects of SARS-CoV-2 infection in cats. 052 ; 080 UR224