%0 Journal Article %9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES %A Fritz, Matthieu %A Nesi, N. %A Denolly, S. %A Boson, B. %A Legros, V. %A Rosolen, S. G. %A Briend-Marchal, A. %A Gouilh, M. A. %A Leroy, Eric %T Detection of SARS-CoV-2 in two cats during the second wave of the COVID-19 pandemic in France %D 2022 %L fdi:010083280 %G ENG %J Veterinary Medicine and Science %K cats ; mild-respiratory clinical signs ; NGS ; One Health ; SARS-CoV-2 ; serology %K FRANCE %M ISI:000711265700001 %N 1 %P 14-20 %R 10.1002/vms3.638 %U https://www.documentation.ird.fr/hor/fdi:010083280 %> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/2021-12/010083280.pdf %V 8 %W Horizon (IRD) %X Although there are several reports in the literature of SARS-CoV-2 infection in cats, few SARS-CoV-2 sequences from infected cats have been published. In this study, SARS-CoV-2 infection was evaluated in two cats by clinical observation, molecular biology (qPCR and NGS), and serology (microsphere immunoassay and seroneutralization). Following the observation of symptomatic SARS-CoV-2 infection in two cats, infection status was confirmed by RT-qPCR and, in one cat, serological analysis for antibodies against N-protein and S-protein, as well as neutralizing antibodies. Comparative analysis of five SARS-CoV-2 sequence fragments obtained from one of the cats showed that this infection was not with one of the three recently emerged variants of SARS-CoV-2. This study provides additional information on the clinical, molecular, and serological aspects of SARS-CoV-2 infection in cats. %$ 052 ; 080