@article{fdi:010083214, title = {{E}mergence and spread of {SARS}-{C}o{V}-2 lineage {B}.1.620 with variant of concern-like mutations and deletions}, author = {{D}udas, {G}. and {H}ong, {S}. {L}. and {P}otter, {B}. {I}. and {C}alvignac-{S}pencer, {S}. and {N}iatou-{S}inga, {F}. {S}. and {T}ombolomako, {T}. {B}. and {F}uh-{N}eba, {T}. and {V}ickos, {U}. and {U}lrich, {M}. and {L}eendertz, {F}. {H}. and {K}han, {K}. and {H}uber, {C}. and {W}atts, {A}. and {O}lendraite, {I}. and {S}nijder, {J}. and {W}ijnant, {K}. {N}. and {B}onvin, {A}.{M}.{J}.{J}. and {M}artres, {P}. and {B}ehillil, {S}. and {A}youba, {A}hidjo and {M}aidadi, {M}. {F}. and {D}jomsi, {D}. {M}. and {G}odwe, {C}. and {B}utel, {C}hristelle and et al.}, editor = {}, language = {{ENG}}, abstract = {{D}istinct {SARS}-{C}o{V}-2 lineages, discovered through various genomic surveillance initiatives, have emerged during the pandemic following unprecedented reductions in worldwide human mobility. {W}e here describe a {SARS}-{C}o{V}-2 lineage - designated {B}.1.620 - discovered in {L}ithuania and carrying many mutations and deletions in the spike protein shared with widespread variants of concern ({VOC}s), including {E}484{K}, {S}477{N} and deletions {HV}69 {D}elta, {Y}144 {D}elta, and {LLA}241/243 {D}elta. {A}s well as documenting the suite of mutations this lineage carries, we also describe its potential to be resistant to neutralising antibodies, accompanying travel histories for a subset of {E}uropean cases, evidence of local {B}.1.620 transmission in {E}urope with a focus on {L}ithuania, and significance of its prevalence in {C}entral {A}frica owing to recent genome sequencing efforts there. {W}e make a case for its likely {C}entral {A}frican origin using advanced phylogeographic inference methodologies incorporating recorded travel histories of infected travellers. {H}ere, the authors describe the emergence and spread of a new potential {SARS}-{C}o{V}-2 variant of interest, {B}.1.620. {T}hey show that this lineage, first identified in {L}ithuania, has established local transmission in {E}urope on multiple occasions and likely emerged in {C}entral {A}frica.}, keywords = {{EUROPE} ; {AFRIQUE} {CENTRALE} ; {CAMEROUN} ; {CENTRAFRIQUE}}, booktitle = {}, journal = {{N}ature {C}ommunications}, volume = {12}, numero = {1}, pages = {5769 [12 ]}, year = {2021}, DOI = {10.1038/s41467-021-26055-8}, URL = {https://www.documentation.ird.fr/hor/fdi:010083214}, }