@article{fdi:010083209,
  title = {{O}n the need for integrating cancer into the {O}ne {H}ealth perspective},
  author = {{D}ujon, {A}. {M}. and {B}rown, {J}. {S}. and {D}estoumieux-{G}arzon, {D}. and {V}ittecoq, {M}. and {H}amede, {R}. and {T}asiemski, {A}. and {B}outry, {J}. and {T}issot, {S}. and {A}lix-{P}anabieres, {C}. and {P}ujol, {P}. and {R}enaud, {F}. and {S}imard, {F}r{\'e}d{\'e}ric and {R}oche, {B}enjamin and {U}jvari, {B}. and {T}homas, {F}.},
  editor = {},
  language = {{ENG}},
  abstract = {{R}ecent pandemics have highlighted the urgency to connect disciplines studying animal, human, and environment health, that is, the "{O}ne {H}ealth" concept. {T}he {O}ne {H}ealth approach takes a holistic view of health, but it has largely focused on zoonotic diseases while not addressing oncogenic processes. {W}e argue that cancers should be an additional key focus in the {O}ne {H}ealth approach based on three factors that add to the well-documented impact of humans on the natural environment and its implications on cancer emergence. {F}irst, human activities are oncogenic to other animals, exacerbating the dynamics of oncogenesis, causing immunosuppressive disorders in wildlife with effects on host-pathogen interactions, and eventually facilitating pathogen spillovers. {S}econd, the emergence of transmissible cancers in animal species (including humans) has the potential to accelerate biodiversity loss across ecosystems and to become pandemic. {I}t is crucial to understand why, how, and when transmissible cancers emerge and spread. {T}hird, translating knowledge of tumor suppressor mechanisms found across the {A}nimal {K}ingdom to human health offers novel insights into cancer prevention and treatment strategies.},
  keywords = {cancer ; comparative oncology ; infectious diseases ; {O}ne {H}ealth ; {P}eto's paradox},
  booktitle = {},
  journal = {{E}volutionary {A}pplications},
  volume = {14},
  numero = {11},
  pages = {2571--2575},
  ISSN = {1752-4571},
  year = {2021},
  DOI = {10.1111/eva.13303},
  URL = {https://www.documentation.ird.fr/hor/fdi:010083209},
}