@article{fdi:010083188,
  title = {{M}ultiple vector-borne pathogens of domestic animals in {E}gypt},
  author = {{A}bdullah, {H}. {H}. {A}. {M}. and {A}manzougaghene, {N}. and {D}ahmana, {H}. and {L}ouni, {M}. and {R}aoult, {D}. and {M}ediannikov, {O}leg},
  editor = {},
  language = {{ENG}},
  abstract = {{A}uthor summary {V}ector {B}orne {D}iseases ({VBD}s) are considered emerging and re-emerging diseases that represent a global burden. {D}iagnosis of these diseases is challenging due to nonspecific febrile illness, difficulty of isolation, and cross-reactivity of serological methods. {T}herefore, the current study is the first large-scale epidemiological study in which molecular screening and characterization of multiple vector-borne pathogens in different animal hosts were performed to better understand the endemicity of {VBD}s in {E}gypt. {W}e detected for the first time {A}naplasma centrale, {A}n. ovis, a novel {A}n. platys-like and {B}orrelia theileri in cattle, a new {A}n. platys-like in buffaloes, {A}n. marginale, {A}n. ovis, a new {A}n. platys-like and {B}o. theileri in sheep, {A}n. platys, a new {A}n. platys-like and {S}etaria digitata in camels and {R}ickettsia africae-like, {A}n. platys, {D}irofilaria repens and {A}canthocheilonema reconditum in dogs, in {E}gypt. {T}hese results imply that ruminants and dogs in {E}gypt are reservoirs for several neglected, emerging and re-emerging potentially new vector-borne pathogens that have significant implications in human health.</p> {V}ector {B}orne {D}iseases ({VBD}s) are considered emerging and re-emerging diseases that represent a global burden. {T}he aim of this study was to explore and characterize vector-borne pathogens in different domestic animal hosts in {E}gypt. {A} total of 557 blood samples were collected from different animals using a convenience sampling strategy (203 dogs, 149 camels, 88 cattle, 26 buffaloes, 58 sheep and 33 goats). {A}ll samples were tested for multiple pathogens using quantitative {PCR} and standard {PCR} coupled with sequencing. {W}e identified {T}heileria annulata and {B}abesia bigemina in cattle (15.9 and 1.1%, respectively), {T}. ovis in sheep and buffaloes (8.6 and 7.7%, respectively) and {B}a. canis in dogs (0.5%) as well as {A}naplasma marginale in cattle, sheep and camels (20.4, 3.4 and 0.7%, respectively) and {C}oxiella burnetii in sheep and goats (1.7 and 3%; respectively). {N}ew genotypes of {A}n. centrale, {A}n. ovis, {A}n. platys-like and {B}orrelia theileri were found in cattle (1.1,3.4, 3.4 and 3.4%, respectively), {A}n. platys-like in buffaloes (7.7%), {A}n. marginale, {A}n. ovis, {A}n. platys-like and {B}o. theileri in sheep (3.4, 1.7, 1.7 and 3.4%, respectively), {A}n. platys, {A}n. platys-like and {S}etaria digitata in camels (0.7, 5.4 and 0.7%, respectively) and {R}ickettsia africae-like, {A}n. platys, {D}irofilaria repens and {A}canthocheilonema reconditum in dogs (1.5, 3.4, 1 and 0.5%, respectively). {C}o-infections were found in cattle, sheep and dogs (5.7, 1.7, 0.5%, respectively). {F}or the first time, we have demonstrated the presence of several vector-borne zoonoses in the blood of domestic animals in {E}gypt. {D}ogs and ruminants seem to play a significant role in the epidemiological cycle of {VBD}s.</p>},
  keywords = {{EGYPTE}},
  booktitle = {},
  journal = {{PL}o{S} {N}eglected {T}ropical {D}iseases},
  volume = {15},
  numero = {9},
  pages = {e0009767 [25 p.]},
  ISSN = {1935-2735},
  year = {2021},
  DOI = {10.1371/journal.pntd.0009767},
  URL = {https://www.documentation.ird.fr/hor/fdi:010083188},
}