%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Simo-Fouda, F.
%A Thirion, Laurence
%A Nougairede, A.
%A Luciani, L.
%A Driouich, J. S.
%A Petit, P. R.
%A Delaunay, P.
%A Charrel, R. N.
%T Investigation of Bufavirus and Parvovirus 4 in patients with gastro-enteritis from the South-East of France
%D 2021
%L fdi:010083187
%G ENG
%J Pathogens
%K bufavirus ; human parvovirus 4 ; Protoparvovirus ; parvovirus ; Parvoviridae ; gastroenteritis ; diarrhea ; France
%K FRANCE
%M ISI:000701851400001
%N 9
%P 1151 [14 ]
%R 10.3390/pathogens10091151
%U https://www.documentation.ird.fr/hor/fdi:010083187
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/2021-11/010083187.pdf
%V 10
%W Horizon (IRD)
%X Bufavirus (BuV) and human parvovirus 4 (PARV4) belong to the Parvoviridae family. We assessed BuV and PARV4 DNA presence by real-time PCR analysis in stool, blood and respiratory samples collected in patients from Marseille and Nice, two large cities in the South-East of France. Bu-V DNA was detected in diarrheic stool samples from 92 patients (3.6% of 2583 patients), particularly men and adults, and patients from the nephrology and the infectious disease departments. Among the patients with a BuV-positive stool sample and for whom at least one blood sample was available (n = 30 patients), BuV DNA was detected also in 3 blood samples. In contrast, BuV DNA was not detected in any of the respiratory samples from 23 patients with BuV-positive stool. BuV detection rate was comparable in stool samples from patients with and without diarrhea. We did not detect PARV4 DNA in any of the stool specimens (n = 2583 patients). Our results suggest that PARV4 fecal-oral transmission is rare or non-existent in the South-East of France while BuV circulates with a relatively high rate in this area.
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