@article{fdi:010083160, title = {{E}valuation of formulations to improve {SARS}-{C}o{V}-2 viability and thermostability after lyophilisation}, author = {{B}aronti, {C}{\'e}cile and {C}outard, {B}. and {L}amballerie, {X}. de and {C}harrel, {R}. and {T}ouret, {F}.}, editor = {}, language = {{ENG}}, abstract = {{I}n the context of the {COVID}-19 pandemic, virus collections such as {EVA}-{GLOBAL} play a key role in the supply of viruses and related products for research. {F}reeze-drying techniques for viruses represent a method of choice for the preservation of strains and their distribution without the need for a demanding cold chain. {H}ere, we describe an optimised lyophilisation protocol usable for {SARS}-{C}o{V}-2 strains that improves preservation and thermostability. {W}e show that sucrose used as an adjuvant represents a simple and efficient stabilizer providing increased protection for long-term preservation and shipment of the virus under different climatic conditions.}, keywords = {{COVID}-19 ; {SARS}-{C}o{V}-2 ; {L}yophilisation ; {S}tabilizers ; {B}iobanking}, booktitle = {}, journal = {{J}ournal of {V}irological {M}ethods}, volume = {297}, numero = {}, pages = {114252 [4 ]}, ISSN = {0166-0934}, year = {2021}, DOI = {10.1016/j.jviromet.2021.114252}, URL = {https://www.documentation.ird.fr/hor/fdi:010083160}, }