@article{fdi:010083075,
  title = {{D}etection of {C}oxiella burnetii and {B}orrelia spp. {DNA} in cutaneous samples and in household dust in rural areas, {S}enegal},
  author = {{D}iouf, {F}. {S}. and {N}diaye, {E}. {I}. and {H}ammoud, {A}. and {D}iamanka, {A}. and {B}assene, {H}. and {N}diaye, {M}. and {M}ediannikov, {O}leg and {P}arola, {P}. and {R}aoult, {D}. and {S}okhna, {C}heikh and {D}iatta, {G}eorges},
  editor = {},
  language = {{ENG}},
  abstract = {{Q} fever and tick-borne borreliosis are two zoonotic diseases rarely diagnosed in {S}enegalese health facilities, particularly in rural areas. {O}ur study aims to better understand the circulation of {C}oxiella burnetii and {B}orrelia spp. {DNA} on human skin and the domestic environment in rural areas. {C}utaneous swabs were taken from febrile patients being treated for borreliosis and/or {Q} fever, the members of patients' households and control households in the {N}iakhar area. {D}ust samples were also collected from 90 households where 54 cases of borreliosis and {Q} fever were reported as well as from the households of members of control populations in {D}ielmo, {N}diop, and {N}iakhar. {C}. burnetii and {B}orrelia spp. {DNA} were detected by quantitative {PCR} in cutaneous swabs and dust samples targeting spacers {IS}1111_{IS}30{A} and {B}or 16{S} gene. {O}f 1365 persons tested, 76 were shown to carry {C}. burnetii, 13 {B}orrelia spp., and 6 were identified as carrying both {C}. burnetii and {B}orrelia spp. {T}he prevalence of {B}orrelia spp. {DNA} in households was 16.7% in {D}ielmo, 6.7% in {N}diop, and 23.3% in all other villages in the {N}iakhar area, and the presence of {C}. burnetii in the same localities was 10%, 13.3% and 66.7%, respectively. {F}urthermore, {C}. burnetii genotyping identified the presence of {M}ultispacer {S}equence {T}yping group 6. {T}hese results revealed for the first time the carriage on the skin of {C}. burnetii and {B}orrelia spp. {DNA} in humans and its wide distribution across households. {O}ur findings suggest that many populations are exposed to these diseases, with frequent contaminating cases of infectious origin arising from the domestic environment.},
  keywords = {{B}acterial {DNA} ; {C}oxiella burnetii ; {B}orrelia spp ; {C}utaneous samples ; {H}ouseholds dust ; {D}omestic environment ; {SENEGAL} ; {NIAKHAR}},
  booktitle = {},
  journal = {{V}ector-{B}orne and {Z}oonotic {D}iseases},
  volume = {21},
  numero = {9},
  pages = {659--666},
  ISSN = {1530-3667},
  year = {2021},
  DOI = {10.1089/vbz.2020.2723},
  URL = {https://www.documentation.ird.fr/hor/fdi:010083075},
}