%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Keita, A. K.
%A Koundouno, F. R.
%A Faye, M.
%A Dux, A.
%A Hinzmann, J.
%A Diallo, H.
%A Ayouba, Ahidjo
%A Le Marcis, Frédéric
%A Soropogui, B.
%A Ifono, K.
%A Diagne, M. M.
%A Sow, M. S.
%A Bore, J. A.
%A Calvignac-Spencer, S.
%A Vidal, Nicole
%A Camara, J.
%A Keita, M. B.
%A Renevey, A.
%A Diallo, A.
%A Soumah, A. K.
%A Millimono, S. L.
%A Mari-Saez, A.
%A Diop, M.
%A Dore, A.
%A Soumah, F. Y.
%A Kourouma, K.
%A Vielle, N. J.
%A Loucoubar, C.
%A Camara, I.
%A Kourouma, K.
%A Annibaldis, G.
%A Bah, A.
%A Thielebein, A.
%A Pahlmann, M.
%A Pullan, S. T.
%A Carroll, M. W.
%A Quick, J.
%A Formenty, P.
%A Legand, A.
%A Pietro, K.
%A Wiley, M. R.
%A Tordo, N.
%A Peyrefitte, C.
%A McCrone, J. T.
%A Rambaut, A.
%A Sidibe, Y.
%A Barry, M. D.
%A Kourouma, M.
%A Saouromou, C. D.
%A Conde, M.
%A Balde, M.
%A Povogui, M.
%A Keita, S.
%A Diakite, M.
%A Bah, M. S.
%A Sidibe, A.
%A Diakite, D.
%A Sako, F. B.
%A Traore, F. A.
%A Ki-Zerbo, G. A.
%A Lemey, P.
%A Gunther, S.
%A Kafetzopoulou, L. E.
%A Sall, A. A.
%A Delaporte, E.
%A Duraffour, S.
%A Faye, O.
%A Leendertz, F. H.
%A Peeters, Martine
%A Toure, A.
%A Magassouba, N. F.
%T Resurgence of Ebola virus in 2021 in Guinea suggests a new paradigm for outbreaks
%D 2021
%L fdi:010082824
%G ENG
%J Nature
%@ 0028-0836
%K GUINEE
%M ISI:000696175300014
%N 7877
%P 539-545
%R 10.1038/s41586-021-03901-9
%U https://www.documentation.ird.fr/hor/fdi:010082824
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/2022-09/010082824.pdf
%V 597
%W Horizon (IRD)
%X Seven years after the declaration of the first epidemic of Ebola virus disease in Guinea, the country faced a new outbreak-between 14 February and 19 June 2021-near the epicentre of the previous epidemic(1,2). Here we use next-generation sequencing to generate complete or near-complete genomes of Zaire ebolavirus from samples obtained from 12 different patients. These genomes form a well-supported phylogenetic cluster with genomes from the previous outbreak, which indicates that the new outbreak was not the result of a new spillover event from an animal reservoir. The 2021 lineage shows considerably lower divergence than would be expected during sustained human-to-human transmission, which suggests a persistent infection with reduced replication or a period of latency. The resurgence of Zaire ebolavirus from humans five years after the end of the previous outbreak of Ebola virus disease reinforces the need for long-term medical and social care for patients who survive the disease, to reduce the risk of re-emergence and to prevent further stigmatization.
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