@article{fdi:010082824, title = {{R}esurgence of {E}bola virus in 2021 in {G}uinea suggests a new paradigm for outbreaks}, author = {{K}eita, {A}. {K}. and {K}oundouno, {F}. {R}. and {F}aye, {M}. and {D}ux, {A}. and {H}inzmann, {J}. and {D}iallo, {H}. and {A}youba, {A}hidjo and {L}e {M}arcis, {F}r{\'e}d{\'e}ric and {S}oropogui, {B}. and {I}fono, {K}. and {D}iagne, {M}. {M}. and {S}ow, {M}. {S}. and {B}ore, {J}. {A}. and {C}alvignac-{S}pencer, {S}. and {V}idal, {N}icole and {C}amara, {J}. and {K}eita, {M}. {B}. and {R}enevey, {A}. and {D}iallo, {A}. and {S}oumah, {A}. {K}. and {M}illimono, {S}. {L}. and {M}ari-{S}aez, {A}. and {D}iop, {M}. and {D}ore, {A}. and {S}oumah, {F}. {Y}. and {K}ourouma, {K}. and {V}ielle, {N}. {J}. and {L}oucoubar, {C}. and {C}amara, {I}. and {K}ourouma, {K}. and {A}nnibaldis, {G}. and {B}ah, {A}. and {T}hielebein, {A}. and {P}ahlmann, {M}. and {P}ullan, {S}. {T}. and {C}arroll, {M}. {W}. and {Q}uick, {J}. and {F}ormenty, {P}. and {L}egand, {A}. and {P}ietro, {K}. and {W}iley, {M}. {R}. and {T}ordo, {N}. and {P}eyrefitte, {C}. and {M}c{C}rone, {J}. {T}. and {R}ambaut, {A}. and {S}idibe, {Y}. and {B}arry, {M}. {D}. and {K}ourouma, {M}. and {S}aouromou, {C}. {D}. and {C}onde, {M}. and {B}alde, {M}. and {P}ovogui, {M}. and {K}eita, {S}. and {D}iakite, {M}. and {B}ah, {M}. {S}. and {S}idibe, {A}. and {D}iakite, {D}. and {S}ako, {F}. {B}. and {T}raore, {F}. {A}. and {K}i-{Z}erbo, {G}. {A}. and {L}emey, {P}. and {G}unther, {S}. and {K}afetzopoulou, {L}. {E}. and {S}all, {A}. {A}. and {D}elaporte, {E}. and {D}uraffour, {S}. and {F}aye, {O}. and {L}eendertz, {F}. {H}. and {P}eeters, {M}artine and {T}oure, {A}. and {M}agassouba, {N}. {F}.}, editor = {}, language = {{ENG}}, abstract = {{S}even years after the declaration of the first epidemic of {E}bola virus disease in {G}uinea, the country faced a new outbreak-between 14 {F}ebruary and 19 {J}une 2021-near the epicentre of the previous epidemic(1,2). {H}ere we use next-generation sequencing to generate complete or near-complete genomes of {Z}aire ebolavirus from samples obtained from 12 different patients. {T}hese genomes form a well-supported phylogenetic cluster with genomes from the previous outbreak, which indicates that the new outbreak was not the result of a new spillover event from an animal reservoir. {T}he 2021 lineage shows considerably lower divergence than would be expected during sustained human-to-human transmission, which suggests a persistent infection with reduced replication or a period of latency. {T}he resurgence of {Z}aire ebolavirus from humans five years after the end of the previous outbreak of {E}bola virus disease reinforces the need for long-term medical and social care for patients who survive the disease, to reduce the risk of re-emergence and to prevent further stigmatization.}, keywords = {{GUINEE}}, booktitle = {}, journal = {{N}ature}, volume = {597}, numero = {7877}, pages = {539--545}, ISSN = {0028-0836}, year = {2021}, DOI = {10.1038/s41586-021-03901-9}, URL = {https://www.documentation.ird.fr/hor/fdi:010082824}, }