@article{fdi:010082766, title = {{L}ack of association between adverse pregnancy outcomes and {Z}ika antibodies among pregnant women in {T}hailand between 1997 and 2015}, author = {{N}go-{G}iang-{H}uong, {N}icole and {L}eroi, {C}. and {F}usco, {D}. and {C}ressey, {T}. {R}. and {W}angsaeng, {N}. and {S}alvadori, {N}. and {K}ongyai, {N}. and {S}irirungsi, {W}. and {L}allemant, {M}arc and {A}uewarakul, {P}. and {K}hamduang, {W}. and {J}ourdain, {G}onzague}, editor = {}, language = {{ENG}}, abstract = {{D}ata about {Z}ika virus infection and adverse pregnancy outcomes in {S}outheast {A}sia are scarce. {W}e conducted an unmatched case-control study of {Z}ika virus ({ZIKV}) serology in pregnant women enrolled in human immunodeficiency virus ({HIV}) or hepatitis {B} virus ({HBV}) perinatal prevention trials between 1997 and 2015 in {T}hailand. {C}ase and control groups included women with and without adverse pregnancy outcomes. {P}lasma samples collected during the last trimester of pregnancy were tested for {ZIKV} {I}g{G}/{I}g{M} and {D}engue {I}g{G}/{I}g{M} ({E}uroimmun, {AG}, {G}ermany). {C}ase newborn plasma samples were tested for {ZIKV} {I}g{M} and {ZIKV} {RNA} ({V}iasure, {S}pain). {T}he case group included women with stillbirth (n = 22) or whose infants had microcephaly (n = 4), a head circumference below the first percentile (n = 14), neurological disorders (n = 36), or had died within 10 days after birth (n = 11). {N}o women in the case group were positive for {ZIKV} {I}g{M}, and none of their live-born neonates were positive for {ZIKV} {I}g{M} or {ZIKV} {RNA}. {T}he overall {ZIKV} {I}g{G} prevalence was 29%, 24% in the case and 34% in the control groups ({F}isher's exact test; p = 0.13), while the dengue {I}g{G} seroprevalence was 90%. {N}either neonatal {ZIKV} infections nor {ZIKV}-related adverse pregnancy outcomes were observed in these women with {HIV} and/or {HBV} during the 18-year study period.}, keywords = {{Z}ika virus ; pregnant women ; adverse pregnancy outcomes ; neonates ; {Z}ika ; virus serology ; dengue virus serology ; {T}hailand ; {THAILANDE}}, booktitle = {}, journal = {{V}iruses}, volume = {13}, numero = {8}, pages = {1423 [8 p.]}, year = {2021}, DOI = {10.3390/v13081423}, URL = {https://www.documentation.ird.fr/hor/fdi:010082766}, }