@article{fdi:010082626,
  title = {{M}etagenomic analysis of nepoviruses : diversity, evolution and identification of a genome region in members of subgroup {A} that appears to be important for host range},
  author = {{H}ily, {J}. {M}. and {P}oulicard, {N}ils and {K}ubina, {J}. and {R}eynard, {J}. {S}. and {S}pilmont, {A}. {S}. and {F}uchs, {M}. and {L}emaire, {O}. and {V}igne, {E}.},
  editor = {},
  language = {{ENG}},
  abstract = {{D}ata mining and metagenomic analysis of 277 open reading frame sequences of bipartite {RNA} viruses of the genus {N}epovirus, family {S}ecoviridae, were performed, documenting how challenging it can be to unequivocally assign a virus to a particular species, especially those in subgroups {A} and {C}, based on some of the currently adopted taxonomic demarcation criteria. {T}his work suggests a possible need for their amendment to accommodate pangenome information. {I}n addition, we revealed a host-dependent structure of arabis mosaic virus ({A}r{MV}) populations at a cladistic level and confirmed a phylogeographic structure of grapevine fanleaf virus ({GFLV}) populations. {W}e also identified new putative recombination events in members of subgroups {A}, {B} and {C}. {T}he evolutionary specificity of some capsid regions of {A}r{MV} and {GFLV} that were described previously and biologically validated as determinants of nematode transmission was circumscribed in silico. {F}urthermore, a {C}-terminal segment of the {RNA}-dependent {RNA} polymerase of members of subgroup {A} was predicted to be a putative host range determinant based on statistically supported higher pi (substitutions per site) values for {GFLV} and {A}r{MV} isolates infecting {V}itis spp. compared with non-{V}itis-infecting {A}r{MV} isolates. {T}his study illustrates how sequence information obtained via high-throughput sequencing can increase our understanding of mechanisms that modulate virus diversity and evolution and create new opportunities for advancing studies on the biology of economically important plant viruses.},
  keywords = {},
  booktitle = {},
  journal = {{A}rchives of {V}irology},
  volume = {166},
  numero = {10},
  pages = {2789--2801},
  ISSN = {0304-8608},
  year = {2021},
  DOI = {10.1007/s00705-021-05111-0},
  URL = {https://www.documentation.ird.fr/hor/fdi:010082626},
}