@article{fdi:010082610, title = {{S}top helping pathogens : engineering plant susceptibility genes for durable resistance}, author = {{G}arcia-{R}uiz, {H}. and {S}zurek, {B}oris and {V}an den {A}ckerveken, {G}.}, editor = {}, language = {{ENG}}, abstract = {{A}lternatives to protect crops against diseases are desperately needed to secure world food production and make agriculture more sustainable. {G}enetic resistance to pathogens utilized so far is mostly based on single dominant resistance genes that mediate specific recognition of invaders and that is often rapidly broken by pathogen variants. {P}erturbation of plant susceptibility ({S}) genes offers an alternative providing plants with recessive resistance that is proposed to be more durable. {S} genes enable the establishment of plant disease, and their inactivation provides opportunities for resistance breeding of crops. {H}owever, loss of {S} gene function can have pleiotropic effects. {D}evelopments in genome editing technology promise to provide powerful methods to precisely interfere with crop {S} gene functions and reduce tradeoffs.}, keywords = {}, booktitle = {}, journal = {{C}urrent {O}pinion in {B}iotechnology}, volume = {70}, numero = {}, pages = {187--195}, ISSN = {0958-1669}, year = {2021}, DOI = {10.1016/j.copbio.2021.05.005}, URL = {https://www.documentation.ird.fr/hor/fdi:010082610}, }