@article{fdi:010082443,
  title = {{A} preoperative nomogram for predicting long-term survival after resection of large hepatocellular carcinoma (sup. 10 cm)},
  author = {{R}uiz, {E}. and {P}ineau, {P}. and {F}lores, {C}. and {F}ernández, {R}. and {C}ano, {L}. and {C}erapio, {J}.{P}. and {C}asavilca-{Z}ambrano, {S}. and {B}errospi, {F}. and {C}hávez, {I}. and {R}oche, {B}enjamin and {B}ertani, {S}t{\'e}phane},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {I}t has previously been demonstrated that a fraction of patients with hepatocellular carcinoma ({HCC}) sup. 10 cm can benefit from liver resection. {H}owever, there is still a lack of effective decision-making tools to inform intervention in these patients. {M}ethods: {W}e analysed a comprehensive set of clinical data from 234 patients who underwent liver resection for {HCC} sup.10 cm at the {N}ational {C}ancer {I}nstitute of {P}eru between 1990 and 2015, monitored their survival, and constructed a nomogram to predict the surgical outcome based on preoperative variables. {R}esults: {W}e identified cirrhosis, multifocality, macroscopic vascular invasion, and spontaneous tumour rupture as independent predictors of survival and integrated them into a nomogram model. {T}he nomogram's ability to forecast survival at 1, 3, and 5 years was subsequently confirmed with high concordance using an internal validation. {T}hrough applying this nomogram, we stratified three groups of patients with different survival probabilities. {C}onclusion: {W}e constructed a preoperative nomogram to predict long-term survival in patients with {HCC} sup.10 cm. {T}his nomogram is useful in determining whether a patient with large {HCC} might truly benefit from liver resection, which is paramount in low- and middle-income countries where {HCC} is often diagnosed at advanced stages.},
  keywords = {{PEROU}},
  booktitle = {},
  journal = {{HPB}},
  volume = {24},
  numero = {2},
  pages = {192--201},
  ISSN = {1365-182{X}},
  year = {2022},
  DOI = {10.1016/j.hpb.2021.06.006},
  URL = {https://www.documentation.ird.fr/hor/fdi:010082443},
}