@article{fdi:010082285,
  title = {{S}oil-transmitted helminth infections in free-ranging non-human primates from {C}ameroon and {G}abon},
  author = {{S}irima, {C}. and {B}izet, {C}harlotte and {H}amou, {H}. and {C}ervena, {B}. and {L}emarcis, {T}homas and {E}steban, {A}mandine and {P}eeters, {M}artine and {N}gole, {E}. {M}. and {M}ombo, {I}. {M}. and {L}i{\'e}geois, {F}lorian and {P}etrzelkova, {K}. {J}. and {B}oussinesq, {M}ichel and {L}ocatelli, {S}abrina},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground {Z}oonotic diseases are a serious threat to both public health and animal conservation. {M}ost non-human primates ({NHP}) are facing the threat of forest loss and fragmentation and are increasingly living in closer spatial proximity to humans. {H}umans are infected with soil-transmitted helminths ({STH}) at a high prevalence, and bidirectional infection with {NHP} has been observed. {T}he aim of this study was to determine the prevalence, genetic diversity, distribution and presence of co-infections of {STH} in free-ranging gorillas, chimpanzees and other {NHP} species, and to determine the potential role of these {NHP} as reservoir hosts contributing to the environmental sustenance of zoonotic nematode infections in forested areas of {C}ameroon and {G}abon. {M}ethods {A} total of 315 faecal samples from six species of {NHP}s were analysed. {W}e performed {PCR} amplification, sequencing and maximum likelihood analysis of {DNA} fragments of the internal transcribed spacer 2 ({ITS}2) nuclear ribosomal {DNA} to detect the presence and determine the genetic diversity of {O}esophagostomum spp., {N}ecator spp. and {T}richuris spp., and of targeted {DNA} fragments of the internal transcribed spacer 1 ({ITS}1) to detect the presence of {A}scaris spp. {R}esults {N}ecator spp. infections were most common in gorillas (35 of 65 individuals), but also present in chimpanzees (100 of 222 individuals) and in one of four samples from greater spot-nosed monkeys. {T}hese clustered with previously described type {II} and {III} {N}ecator spp. {G}orillas were also the most infected {NHP} with {O}esophagostomum (51/65 individuals), followed by chimpanzees (157/222 individuals), mandrills (8/12 samples) and mangabeys (7/12 samples), with {O}. stephanostomum being the most prevalent species. {O}esophagostomum bifurcum was detected in chimpanzees and a red-capped mangabey, and a non-classified {O}esophagostomum species was detected in a mandrill and a red-capped mangabey. {I}n addition, {T}ernidens deminutus was detected in samples from one chimpanzee and three greater spot-nosed monkeys. {A} significant relative overabundance of co-infections with {N}ecator and {O}esophagostomum was observed in chimpanzees and gorillas. {T}richuris sp. was detected at low prevalence in a gorilla, a chimpanzee and a greater spot-nosed monkey. {N}o {A}scaris was observed in any of the samples analysed. {C}onclusions {O}ur results on {STH} prevalence and genetic diversity in {NHP} from {C}ameroon and {G}abon corroborate those obtained from other wild {NHP} populations in other {A}frican countries. {F}uture research should focus on better identifying, at a molecular level, the species of {N}ecator and {O}esophagostomum infecting {NHP} and determining how human populations may be affected by increased proximity resulting from encroachment into sylvatic {STH} reservoir habitats.},
  keywords = {{S}oil-transmitted helminths ; {N}on-human primate ; {A}frica ; {Z}oonosis ; {P}hylogeny ; {F}aeces ; {CAMEROUN} ; {GABON}},
  booktitle = {},
  journal = {{P}arasites and {V}ectors},
  volume = {14},
  numero = {1},
  pages = {354 [18 p.]},
  ISSN = {1756-3305},
  year = {2021},
  DOI = {10.1186/s13071-021-04855-7},
  URL = {https://www.documentation.ird.fr/hor/fdi:010082285},
}