@article{fdi:010082172,
  title = {{O}rgan geometry channels reproductive cell fate in the {A}rabidopsis ovule primordium},
  author = {{H}ernandez-{L}agana, {E}. and {M}osca, {G}. and {M}endocilla-{S}ato, {E}. and {P}ires, {N}. and {F}rey, {A}. and {G}iraldo-{F}onseca, {A}. and {M}ichaud, {C}aroline and {G}rossniklaus, {U}. and {H}amant, {O}. and {G}odin, {C}. and {B}oudaoud, {A}. and {G}rimanelli, {D}aniel and {A}utran, {D}aphn{\'e} and {B}aroux, {C}.},
  editor = {},
  language = {{ENG}},
  abstract = {{I}n multicellular organisms, sexual reproduction requires the separation of the germline from the soma. {I}n flowering plants, the female germline precursor differentiates as a single spore mother cell ({SMC}) as the ovule primordium forms. {H}ere, we explored how organ growth contributes to {SMC} differentiation. {W}e generated 92 annotated 3{D} images at cellular resolution in {A}rabidopsis. {W}e identified the spatio-temporal pattern of cell division that acts in a domain-specific manner as the primordium forms. {T}issue growth models uncovered plausible morphogenetic principles involving a spatially confined growth signal, differential mechanical properties, and cell growth anisotropy. {O}ur analysis revealed that {SMC} characteristics first arise in more than one cell but {SMC} fate becomes progressively restricted to a single cell during organ growth. {A}ltered primordium geometry coincided with a delay in the fate restriction process in katanin mutants. {A}ltogether, our study suggests that tissue geometry channels reproductive cell fate in the {A}rabidopsis ovule primordium.},
  keywords = {},
  booktitle = {},
  journal = {e{L}ife},
  volume = {10},
  numero = {},
  pages = {e66031 [46 p.]},
  ISSN = {2050-084{X}},
  year = {2021},
  DOI = {10.7554/e{L}ife.66031},
  URL = {https://www.documentation.ird.fr/hor/fdi:010082172},
}