@article{fdi:010082048, title = {{T}he origin of island populations of the {A}frican malaria mosquito, {A}nopheles coluzzii}, author = {{C}ampos, {M}. and {H}anemaaijer, {M}. and {G}ripkey, {H}. and {C}ollier, {T}. {C}. and {L}ee, {Y}. {S}. and {C}ornel, {A}. {J}. and {P}into, {J}. and {A}yala, {D}iego and {R}ompao, {H}. and {L}anzaro, {G}. {C}.}, editor = {}, language = {{ENG}}, abstract = {{A}nopheles coluzzii is a major malaria vector throughout its distribution in west-central {A}frica. {H}ere we present a whole-genome study of 142 specimens from nine countries in continental {A}frica and three islands in the {G}ulf of {G}uinea. {T}his sample set covers a large part of this species' geographic range. {O}ur population genomic analyses included a description of the structure of mainland populations, island populations, and connectivity between them. {T}hree genetic clusters are identified among mainland populations and genetic distances ({F}-{ST}) fits an isolation-by-distance model. {G}enomic analyses are applied to estimate the demographic history and ancestry for each island. {T}aken together with the unique biogeography and history of human occupation for each island, they present a coherent explanation underlying levels of genetic isolation between mainland and island populations. {W}e discuss the relationship of our findings to the suitability of {S}ao {T}ome and {P}rincipe islands as candidate sites for potential field trials of genetic-based malaria control strategies. {C}ampos, {L}anzaro and colleagues use whole-genome sequencing and population genomic analyses to infer connectivity between mainland and island mosquito populations in {W}est {A}frica. {T}he unique biogeographic history for each island population is reported, and the findings highlight potential candidate sites for genetic-based malaria control strategies.}, keywords = {{AFRIQUE} {DE} {L}'{OUEST} ; {AFRIQUE} {CENTRALE} ; {GUINEE} {EQUATORIALE} ; {ANGOLA} ; {BENIN} ; {BURKINA} {FASO} ; {COTE} {D}'{IVOIRE} ; {GABON} ; {GHANA} ; {MALI} ; {CAMEROUN} ; {SAO} {TOME} {E} {PRINCIPE} ; {BIOKO} ; {GUINEE} {GOLFE} ; {GUINEA}}, booktitle = {}, journal = {{C}ommunications {B}iology}, volume = {4}, numero = {1}, pages = {630 [9 ]}, year = {2021}, DOI = {10.1038/s42003-021-02168-0}, URL = {https://www.documentation.ird.fr/hor/fdi:010082048}, }