@article{fdi:010082042, title = {{S}mall {RNA}s guide histone methylation in {A}rabidopsis embryos}, author = {{P}arent, {J}. {S}. and {C}ahn, {J}. and {H}erridge, {R}. {P}. and {G}rimanelli, {D}aniel and {M}artienssen, {R}. {A}.}, editor = {}, language = {{ENG}}, abstract = {{E}pigenetic reprogramming occurs during gametogenesis as well as during embryogenesis to reset the genome for early development. {I}n flowering plants, many heterochromatic marks are maintained in sperm, but asymmetric {DNA} methylation is mostly lost. {A}symmetric {DNA} methylation is dependent on small {RNA} but the re-establishment of silencing in embryo is not well understood. {H}ere we demonstrate that small {RNA}s direct the histone {H}3 lysine 9 dimethylation during {A}rabidopsis thaliana embryonic development, together with asymmetric {DNA} methylation. {T}his de novo silencing mechanism depends on the catalytic domain of {SUVH}9, a {S}u({V}ar)3-9 homolog thought to be catalytically inactive.}, keywords = {epigenetic reprogramming ; small {RNA} molecules ; {DNA} methylation ; plant embryogenesis ; histone methylation}, booktitle = {}, journal = {{G}enes and {D}evelopment}, volume = {35}, numero = {11-12}, pages = {841--846}, ISSN = {0890-9369}, year = {2021}, DOI = {10.1101/gad.343871.120}, URL = {https://www.documentation.ird.fr/hor/fdi:010082042}, }