@article{fdi:010081474,
  title = {{E}pidemiological and entomological studies of malaria transmission in {T}ibati, {A}damawa region of {C}ameroon 6 years following the introduction of long-lasting insecticide nets [+ {C}orrection : 2021,14,512]},
  author = {{F}eufack-{D}onfack, {L}. {B}. and {S}arah-{M}atio, {E}. {M}. and {A}bate, {L}. {M}. and {T}uedom, {A}. {G}. {B}. and {B}ayibeki, {A}. {N}. and {N}gou, {C}. {M}. and {T}oto, {J}. {C}. and {S}andeu, {M}. {M}. and {M}oukoko, {C}. {E}. {E}. and {A}yong, {L}. and {A}wono-{A}mbene, {P}. and {M}orlais, {I}sabelle and {N}sango, {S}. {E}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {M}alaria remains a serious public health problem in {C}ameroon. {I}mplementation of control interventions requires prior knowledge of the local epidemiological situation. {H}ere we report the results of epidemiological and entomological surveys carried out in {T}ibati, {A}damawa {R}egion, {C}ameroon, an area where malaria transmission is seasonal, 6 years after the introduction of long-lasting insecticidal bed nets. {M}ethods: {C}ross-sectional studies were carried out in {J}uly 2015 and 2017 in {T}ibati. {T}hick blood smears and dried blood spots were collected from asymptomatic and symptomatic individuals in the community and at health centers, respectively, and used for the molecular diagnosis of {P}lasmodium species. {A}dult mosquitoes were collected by indoor residual spraying and identified morphologically and molecularly. {T}he infection status of {P}lasmodium spp. was determined by quantitative {PCR}, and positivity of {PCR}-positive samples was confirmed by {S}anger sequencing. {R}esults: {O}verall malaria prevalence in our study population was 55.0% (752/1367) and {P}lasmodium falciparum was the most prevalent parasite species (94.3%), followed by {P}. malariae (17.7%) and {P}. ovale (0.8%); 92 (12.7%) infections were mixed infections. {I}nfection parameters varied according to clinical status (symptomatic/asymptomatic) and age of the sampled population and the collection sites. {I}nfection prevalence was higher in asymptomatic carriers (60.8%), but asexual and sexual parasite densities were lower. {P}revalence and intensity of infection decreased with age in both the symptomatic and asymptomatic groups. {H}eterogeneity in infections was observed at the neighborhood level, revealing hotspots of transmission. {A}mong the 592 {A}nopheles mosquitoes collected, 212 (35.8%) were {A}n. gambiae, 172 (29.1%) were {A}n. coluzzii and 208 (35.1%) were {A}n. funestus (s.s.). {A} total of 26 (4.39%) mosquito specimens were infected by {P}lasmodium sp. and the three {A}nopheles mosquitoes transmitted {P}lasmodium at equal efficiency. {S}urprisingly, we found an {A}n. coluzzii specimen infected by {P}lasmodium vivax, which confirms circulation of this species in {C}ameroon. {T}he positivity of all 26 {PCR}-positive {P}lasmodium-infected mosquitoes was successively confirmed by sequencing analysis. {C}onclusion: {O}ur study presents the baseline malaria parasite burden in {T}ibati, {A}damawa {R}egion, {C}ameroon. {O}ur results highlight the high malaria endemicity in the area, and hotspots of disease transmission are identified. {P}arasitological indices suggest low bednet usage and that implementation of control interventions in the area is needed to reduce malaria burden. {W}e also report for the first time a mosquito vector with naturally acquired {P}. vivax infection in {C}ameroon.},
  keywords = {{M}alaria ; {P}lasmodium vivax ; {A}nopheles coluzzii ; {E}pidemiology ; {E}ntomology ; {C}ameroon ; {CAMEROUN} ; {ADAMAWA} ; {TIBATI}},
  booktitle = {},
  journal = {{P}arasites and {V}ectors},
  volume = {14},
  numero = {1},
  pages = {247 [14  + {C}orrection : 2021,14,512]},
  ISSN = {1756-3305},
  year = {2021},
  DOI = {10.1186/s13071-021-04745-y},
  URL = {https://www.documentation.ird.fr/hor/fdi:010081474},
}