@article{fdi:010081385,
  title = {{C}ytokine response following perturbation of the cervicovaginal milieu during {HPV} genital infection},
  author = {{S}elinger, {C}hristian and {R}ahmoun, {M}. and {M}urall, {C}. {L}. and {B}ernat, {C}. and {B}oue, {V}. and {B}onneau, {M}. and {G}raf, {C}. and {G}rasset, {S}. and {G}roc, {S}. and {R}eynes, {J}. and {H}irtz, {C}. and {J}acobs, {N}. and {A}lizon, {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{H}uman papillomaviruses ({HPV}s) are oncogenic viruses causing most cervical cancers. {H}ighly prevalent in young, sexually active women, only a minority of {HPV} infections persist. {T}o better characterize the immuno-modulatory impact of early {HPV} infections, we measured changes in a panel of 20 cytokines in cervicovaginal samples collected from young women who were tested for {HPV} and self-reported for genital inflammation and infection symptoms. {M}ulti-factor statistical analyses revealed that increased {IL}-1{A}lpha and {IL}-12/{IL}-23p40 concentrations were associated with {HPV} infection and that macrophage inflammatory proteins were associated in particular with high-risk {HPV} infections. {C}linical{T}rials.gov identifier {NCT}02946346},
  keywords = {{H}uman papillomavirus ; {C}ytokines ; {N}atural history ; {M}ucosal immunity ; {FRANCE} ; {MONTPELLIER}},
  booktitle = {},
  journal = {{I}mmunologic {R}esearch},
  volume = {[{E}arly access]},
  numero = {},
  pages = {[9 ]},
  ISSN = {0257-277{X}},
  year = {2021},
  DOI = {10.1007/s12026-021-09196-2},
  URL = {https://www.documentation.ird.fr/hor/fdi:010081385},
}