@article{fdi:010081254,
  title = {{F}irst investigation of pathogenic bacteria, protozoa and viruses in rodents and shrews in context of forest-savannah-urban areas interface in the city of {F}ranceville ({G}abon)},
  author = {{M}angombi, {J}. {B}. and {N}'{D}ilimabaka, {N}. and {L}ekana-{D}ouki, {J}. {B}. and {B}anga, {O}. and {M}aghendji-{N}zondo, {S}. and {B}ourgarel, {M}. and {L}eroy, {E}ric and {F}enollar, {F}. and {M}ediannikov, {O}leg},
  editor = {},
  language = {{ENG}},
  abstract = {{R}odents are reservoirs of numerous zoonotic diseases caused by bacteria, protozoans, or viruses. {I}n {G}abon, the circulation and maintenance of rodent-borne zoonotic infectious agents are poorly studied and are often limited to one type of pathogen. {A}mong the three existing studies on this topic, two are focused on a zoonotic virus, and the third is focused on rodent {P}lasmodium. {I}n this study, we searched for a wide range of bacteria, protozoa and viruses in different organs of rodents from the town of {F}ranceville in {G}abon. {S}amples from one hundred and ninety-eight (198) small mammals captured, including two invasive rodent species, five native rodent species and 19 shrews belonging to the {S}oricidae family, were screened. {T}he investigated pathogens were bacteria from the {R}ickettsiaceae and {A}naplasmataceae families, {M}ycoplasma spp., {B}artonella spp., {B}orrelia spp., {O}rientia spp., {O}ccidentia spp., {L}eptospira spp., {S}treptobacillus moniliformis, {C}oxiella bumetii, and {Y}ersinia pestis; parasites from class {K}inetoplastida spp. ({L}eishmania spp., {T}rypanosoma spp.), {P}iroplasmidae spp., and {T}oxoplasma gondii; and viruses from {P}aramyxoviridae, {H}antaviridae, {F}laviviridae and {M}ammarenavirus spp. {W}e identified the following pathogenic bacteria: {A}naplasma spp. (8.1%; 16/198), {B}artonella spp. (6.6%; 13/198), {C}oxiella spp. (5.1%; 10/198) and {L}eptospira spp. (3.5%; 7/198); and protozoans: {P}iroplasma sp. (1%; 2/198), {T}oxoplasma gondii (0.5%; 1/198), and {T}rypanosoma sp. (7%; 14/198). {N}one of the targeted viral genes were detected. {T}hese pathogens were found in {G}abonese rodents, mainly {L}ophuromys sp., {L}emniscomys striatus and {P}raomys sp. {W}e also identified new genotypes: {C}andidatus {B}artonella gabonensis and {U}ncultured {A}naplasma spp. {T}his study shows that rodents in {G}abon harbor some human pathogenic bacteria and protozoans. {I}t is necessary to determine whether the identified microorganisms are capable of undergoing zoonotic transmission from rodents to humans and if they may be responsible for human cases of febrile disease of unknown etiology in {G}abon.},
  keywords = {{GABON} ; {FRANCEVILLE}},
  booktitle = {},
  journal = {{PL}o{S} {O}ne},
  volume = {16},
  numero = {3},
  pages = {e0248244 [28 p.]},
  ISSN = {1932-6203},
  year = {2021},
  DOI = {10.1371/journal.pone.0248244},
  URL = {https://www.documentation.ird.fr/hor/fdi:010081254},
}