@article{fdi:010081023,
  title = {{N}atural infection of free-ranging mandrills ({M}andrillus sphinx) by enteroviruses and astroviruses in southern {G}abon},
  author = {{M}ombo, {I}. {M}. and {B}oundenga, {L}. and {S}uquet, {E}. and {N}goubangoye, {B}. and {M}aganga, {G}. {D}. and {L}eroy, {E}ric and {C}harpentier, {M}. {J}. and {R}ougeron, {V}.},
  editor = {},
  language = {{ENG}},
  abstract = {{E}nteroviruses ({P}icornaviridae) and astroviruses ({A}stroviridae) cause various diseases in humans and animals, including in non-human primates ({NHP}s). {S}ome enteroviruses and astroviruses detected in {NHP}s are genetically related to those infecting humans, indicating the occurrence of interspecies transmissions. {I}n this study, we screened 200 fecal samples of 56 free-ranging mandrills ({M}andrillus sphinx) by nested reverse transcription-{PCR} with primers targeting the {VPI} and {R}d{R}p genes, to evaluate the diversity of enterovirus and astrovirus infection, respectively, and the associated zoonotic risk. {O}verall, ten samples from six mandrills were enterovirus-positive (5%), and three samples from three mandrills were astrovirus-positive (1.5%). {T}his is the first evidence of astrovirus infection in mandrills. {P}hylogenetic analyses based on the {VPI} sequences revealed that all ten enterovirus sequences were part of the species {E}nterovirus {J}, suggesting low zoonotic risk. {P}hylogenetic analysis of the three astrovirus sequences showed that they all belonged to the {M}amastrovirus genus. {T}wo astrovirus sequences were highly divergent from all human astrovirus sequences (63.4-73% nucleotide identity), while one sequence ({A}st{V}-5) suggested cross-species transmission from humans to mandrills. {A}dditional studies are needed to better characterize the identified astroviruses and to confirm whether mandrills are host of astroviruses than can be transmitted to humans.},
  keywords = {{M}andrills ; {C}ross-species transmission ; {E}nteroviruses ; {A}stroviruses ; {GABON}},
  booktitle = {},
  journal = {{M}icrobial {P}athogenesis},
  volume = {150},
  numero = {},
  pages = {104659 [6 p.]},
  ISSN = {0882-4010},
  year = {2021},
  DOI = {10.1016/j.micpath.2020.104659},
  URL = {https://www.documentation.ird.fr/hor/fdi:010081023},
}