@article{fdi:010080794,
  title = {{A}ltitude and hillside orientation shapes the population structure of the {L}eishmania infantum vector {P}hlebotomus ariasi},
  author = {{P}rudhomme, {J}. and {D}e {M}eeûs, {T}hierry and {T}oty, {C}{\'e}line and {C}assan, {C}{\'e}cile and {R}ahola, {N}il and {V}ergnes, {B}aptiste and {C}harrel, {R}. and {A}lten, {B}. and {S}ereno, {D}enis and {B}anuls, {A}nne-{L}aure},
  editor = {},
  language = {{ENG}},
  abstract = {{D}espite their role in {L}eishmania transmission, little is known about the organization of sand fly populations in their environment. {H}ere, we used 11 previously described microsatellite markers to investigate the population genetic structure of {P}hlebotomus ariasi, the main vector of {L}eishmania infantum in the region of {M}ontpellier ({S}outh of {F}rance). {F}rom {M}ay to {O}ctober 2011, we captured 1,253 {P}h. ariasi specimens using sticky traps in 17 sites in the {N}orth of {M}ontpellier along a 14-km transect, and recorded the relevant environmental data (e.g., altitude and hillside). {A}mong the selected microsatellite markers, we removed five loci because of stutter artifacts, absence of polymorphism, or non-neutral evolution. {M}ultiple regression analyses showed the influence of altitude and hillside (51% and 15%, respectively), and the absence of influence of geographic distance on the genetic data. {T}he observed significant isolation by elevation suggested a population structure of {P}h. ariasiorganized in altitudinal ecotypes with substantial rates of migration and positive assortative mating. {T}his organization has implications on sand fly ecology and pathogen transmission. {I}ndeed, this structure might favor the global temporal and spatial stability of sand fly populations and the spread and increase of {L}. infantum cases in {F}rance. {O}ur results highlight the necessity to consider sand fly populations at small scales to study their ecology and their impact on pathogens they transmit},
  keywords = {{FRANCE} ; {HERAULT}},
  booktitle = {},
  journal = {{S}cientific {R}eports - {N}ature},
  volume = {10},
  numero = {1},
  pages = {14443 [13 ]},
  ISSN = {2045-2322},
  year = {2020},
  DOI = {10.1038/s41598-020-71319-w},
  URL = {https://www.documentation.ird.fr/hor/fdi:010080794},
}