@article{fdi:010080648, title = {{I}nsecticide resistance status of malaria vectors {A}nopheles gambiae (s.l.) of southwest {B}urkina {F}aso and residual efficacy of indoor residual spraying with microencapsulated pirimiphos-methyl insecticide}, author = {{S}oma, {D}. {D}. and {Z}ogo, {B}. and {H}ien, {D}. {F}. {D}. and {H}ien, {A}. {S}. and {K}abore, {D}. {A}. and {K}ientega, {M}. and {O}uedraogo, {A}. {G}. and {P}ennetier, {C}{\'e}dric and {K}offi, {A}. {A}. and {M}oiroux, {N}icolas and {D}abire, {R}. {K}.}, editor = {}, language = {{ENG}}, abstract = {{B}ackground{T}he rapid spread of insecticide resistance in malaria vectors and the rebound in malaria cases observed recently in some endemic areas underscore the urgent need to evaluate and deploy new effective control interventions. {A} randomized control trial ({RCT}) was conducted with the aim to investigate the benefit of deploying complementary strategies, including indoor residual spraying ({IRS}) with pirimiphos-methyl in addition to long-lasting insecticidal nets ({LLIN}s) in {D}iebougou, southwest {B}urkina {F}aso.{M}ethods{W}e measured the susceptibility of the {A}nopheles gambiae (s.l.) population from {D}iebougou to conventional insecticides. {W}e further monitored the efficacy and residual activity of pirimiphos-methyl on both cement and mud walls using a laboratory susceptible strain ({K}isumu) and the local {A}n. gambiae (s.l.) population.{R}esults{A}n. gambiae (s.l.) from {D}iebougou was resistant to {DDT}, pyrethroids (deltamethrin, permethrin and alphacypermethrin) and bendiocarb but showed susceptibility to organophosphates (pirimiphos-methyl and chlorpyrimiphos-methyl). {A} mixed-effect generalized linear model predicted that pirimiphos-methyl applied on cement or mud walls was effective for 210 days against the laboratory susceptible strain and 247 days against the local population. {T}he residual efficacy of pirimiphos-methyl against the local population on walls made of mud was similar to that of cement ({OR}=0.792, [0.55-1.12], {T}ukey's test p-value=0.19).{C}onclusions{I}f data on malaria transmission and malaria cases (as measured trough the {RCT}) are consistent with data on residual activity of pirimiphos-methyl regardless of the type of wall, one round of {IRS} with pirimiphos-methyl would have the potential to control malaria in a context of multi-resistant {A}n. gambiae (s.l.) for at least 7 months.}, keywords = {{V}ector control ; {R}esistance ; {C}hemical analysis ; {B}urkina {F}aso ; {IRS} ; {BURKINA} {FASO}}, booktitle = {}, journal = {{P}arasites and {V}ectors}, volume = {14}, numero = {1}, pages = {58 [9 ]}, ISSN = {1756-3305}, year = {2021}, DOI = {10.1186/s13071-020-04563-8}, URL = {https://www.documentation.ird.fr/hor/fdi:010080648}, }