@article{fdi:010080490 ,
  title = {{A}cute kidney failure following severe viper envenomation : clinical, biological and ultrasonographic aspects},
  author = {{T}chaou, {B}. {A}. and de {T}ove, {K}. {M}. {S}. and {N}'{V}enonfon, {C}. {F}. {T}. and {M}fin, {P}. {K}. and {A}guemon, {A}. {R}. and {C}hobli, {M}. and {C}hippaux, {J}ean-{P}hilippe},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {A}cute kidney injury ({AKI}) is a frequent complication of snakebite envenomation, which is still little known in sub-{S}aharan {A}frica. {T}his study aims to describe the clinical, biological and ultrasonographic aspects of {AKI} following severe snakebite envenomation managed in the intensive care unit. {M}ethod: {A} prospective observational survey was performed in {B}enin over a period of 18 months. {A}ll patients suffering severe snakebite envenomation ({SBE}) were included. {T}he diagnosis of {AKI} was made using the {KDIGO} criteria. {K}idney ultrasound exam was performed in all patients to assess internal bleeding and morphological and structural abnormalities of the kidneys. {R}esults: {F}ifty-one cases of severe {SBE} were included. {A}ll patients presented inflammatory syndrome and showed abnormal {WBCT} whereas bleeding was found in 46 of them (90%). {T}he median time to hospital presentation was three days. {T}he majority of patients were male ({M}/{F} sex ratio = 1.55) and the median age was 26. {S}ixteen patients (31%) showed {AKI} according to the {KDIGO} criteria. {S}evere {AKI} ({KDIGO} stage 2 and 3) was observed in three patients, including one stage 2 and two stage 3. {K}idney ultrasound revealed three cases of kidney capsular hematoma (6%), two cases of kidney hypertrophy (3%), three cases of kidney injury (4%), two stage 1 {KDIGO} and one stage 2 {KDIGO}. {O}nly one patient benefited from hemodialysis. {A}ll patients showing {AKI} recovered without sequels. {T}he median duration of hospital stays was four days. {S}even patients died (14%) including four among the 16 {AKI} patients. {A}ntivenom has been administered to 41 patients (80%). {T}he comparison between patients without and with {AKI} did not show any significant difference except gender (p = 10(-)(2)). {C}onclusion: {AKI} is a common complication of severe snakebite envenomation. {R}esulting from inflammatory and hemorrhagic disorders, {AKI} may prove to be a short-term life-threatening factor.},
  keywords = {{E}nvenomation ; {S}nakebite ; {A}ntivenom ; {A}cute kidney injury ; {KDIGO} ; {S}ubcapsular hematoma ; {H}emorrhagic syndrome ; {B}enin ; {BENIN}},
  booktitle = {},
  journal = {{J}ournal of {V}enomous {A}nimals and {T}oxins {I}ncluding {T}ropical {D}iseases},
  volume = {26},
  numero = {},
  pages = {{E}20200059 [12p.]},
  year = {2020},
  DOI = {10.1590/1678-9199-jvatitd-2020-0059},
  URL = {https://www.documentation.ird.fr/hor/fdi:010080490 },
}