Aghokeng Fobang Avelin, Mpoudi-Ngole E., Chia J. E., Edoul E. M., Delaporte Eric, Peeters Martine. (2011). High failure rate of the ViroSeq HIV-1 genotyping system for drug resistance testing in Cameroon, a country with broad HIV-1 genetic diversity. Journal of Clinical Microbiology, 49 (4), p. 1635-1641. ISSN 0095-1137.
Titre du document
High failure rate of the ViroSeq HIV-1 genotyping system for drug resistance testing in Cameroon, a country with broad HIV-1 genetic diversity
Aghokeng Fobang Avelin, Mpoudi-Ngole E., Chia J. E., Edoul E. M., Delaporte Eric, Peeters Martine
Source
Journal of Clinical Microbiology, 2011,
49 (4), p. 1635-1641 ISSN 0095-1137
The ViroSeq HIV-1 genotyping system is used in many African countries for drug resistance testing. In this study, we used a panel of diverse HIV-1 group M isolates circulating in Cameroon to show that the performance of this assay can be altered by the sequence variation of non-B HIV-1 strains that predominate in African settings.