@article{fdi:010080001,
  title = {{T}ransmissible cancers in mammals and bivalves : how many examples are there ? {P}redictions indicate widespread occurrence},
  author = {{D}ujon, {A}. {M}. and {B}ramwell, {G}. and {R}oche, {B}enjamin and {T}homas, {F}. and {U}jvari, {B}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}ransmissible cancers are elusive and understudied parasitic life forms caused by malignant clonal cells (nine lineages are known so far). {T}hey emerge by completing sequential steps that include breaking cell cooperation, evade anti-cancer defences and shedding cells to infect new hosts. {T}ransmissible cancers impair host fitness, and their importance as selective force is likely largely underestimated. {I}t is, therefore, crucial to determine how common they might be in the wild. {H}ere, we draw a parallel between the steps required for a transmissible cancer to emerge and the steps required for an intelligent civilisation to emerge in the {M}ilky {W}ay using a modified {D}rake equation. {U}sing numerical analyses, we estimate the potential number of extant marine and bivalve species in which transmissible cancers might exist. {O}ur results suggest that transmissible cancers are more common than expected, and that new lineages can be found by screening a large number of species.},
  keywords = {disease outbreaks ; epidemiology ; extra&#8208 ; terrestrial life ; {F}ermi paradox ; infectious disease ; neoplasm},
  booktitle = {},
  journal = {{B}ioessays},
  volume = {43},
  numero = {3},
  pages = {2000222 [10 ]},
  ISSN = {0265-9247},
  year = {2020},
  URL = {https://www.documentation.ird.fr/hor/fdi:010080001},
}