Perrin A. auteur aut IRD Gosselin-Grenet A. S. auteur aut IRD Rossignol Marie auteur aut IRD Ginibre Carole auteur aut IRD Scheid Bethsabée auteur aut IRD Lagneau C. auteur aut IRD Chandre Fabrice auteur aut IRD Baldet T. auteur aut IRD Ogliastro M. auteur aut IRD Bouyer J. auteur aut IRD text journalArticle eng text/pdf reformatted digital access Urban Aedes mosquitoes are vectors of many viruses affecting human health such as dengue, chikungunya and Zika viruses. Insecticide resistance and environmental toxicity risks hamper the effectiveness of chemical control against these mosquito vectors. Alternative control methods, such as the use of mosquito-specific entomopathogenic viruses should be explored. Numerous studies have focused on evaluating the potential of different densoviruses species as biological control agents. However, knowledge on the extent of inter- and intra-specific variations in the susceptibility of Aedes mosquitoes to infection by different densoviruses remains insufficient. In this study, we compared infection and mortality rates induced by the Aedes albopictus densovirus 2 in different strains of Aedes albopictus and Aedes aegypti mosquitoes. The two Aedes species were different in terms of susceptibility to viral infection. Under laboratory conditions, Aedes albopictus densovirus 2 appeared more virulent for the different strains of Aedes aegypti tested than for those of Aedes albopictus. In addition, we also found significant intra-specific variation in infection and mortality rates. Thus, although even if Aedes albopictus densoviruses could be powerful biocontrol agents used in the management of urban Aedes populations, our results also call into question the use of single viral isolate as biocontrol agents. specialized 052 102 10 1 18654 [8 ] 2020 2045-2322 https://www.documentation.ird.fr/hor/fdi:010079985 2045-2322 [F B010079985] https://www.documentation.ird.fr/hor/fdi:010079985 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-12/010079985.pdf IRD - Base Horizon / Pleins textes 2021-01-14 2021-01-18 fdi:010079985 fre