@article{fdi:010079970,
  title = {{M}onitoring insecticide susceptibility in {A}edes {A}egypti populations from the two biggest cities, {O}uagadougou and {B}obo-{D}ioulasso, in {B}urkina {F}aso : implication of metabolic resistance},
  author = {{N}amountougou, {M}. and {S}oma, {D}. {D}. and {B}albone, {M}. and {K}abore, {D}. {A}. and {K}ientega, {M}. and {H}ien, {A}. and {C}oulibaly, {A}. and {O}uattara, {P}. {E}. and {M}eda, {B}. {G}. and {D}rabo, {S}. and {K}oala, {L}. and {N}ignan, {C}. and {K}agone, {T}. and {D}iabate, {A}. and {F}ournet, {F}lorence and {G}nankine, {O}. and {D}abire, {R}. {K}.},
  editor = {},
  language = {{ENG}},
  abstract = {{I}n {W}est {A}frica, {A}edes aegypti remains the major vector of dengue virus. {S}ince 2013, dengue fever has been reemerging in {B}urkina {F}aso with annual outbreaks, thus becoming a major public health problem. {I}ts control relies on vector control, which is unfortunately facing the problem of insecticide resistance. {A}t the time of this study, although data on phenotypic resistance were available, information related to the metabolic resistance in {A}edes populations from {B}urkina {F}aso remained very scarce. {H}ere, we assessed the phenotypic and the metabolic resistance of {A}e. aegypti populations sampled from the two main urban areas ({O}uagadougou and {B}obo-{D}ioulasso) of {B}urkina {F}aso. {I}nsecticide susceptibility bioassays to chlorpyriphos-methyl 0.4%, bendiocarb 0.1% and deltamethrin 0.05% were performed on natural populations of {A}e. aegypti using the {WHO} protocol. {T}he activity of enzymes involved in the rapid detoxification of insecticides, especially non-specific esterases, oxidases (cytochrome {P}450) and glutathione-{S}-transferases, was measured on individual mosquitos. {T}he mortality rates for deltamethrin 0.05% were low and ranged from 20.72% to 89.62% in the {B}obo-{D}ioulasso and {O}uagadougou sites, respectively. {W}hen bendiocarb 0.1% was tested, the mortality rates ranged from 7.73% to 71.23%. {I}nterestingly, in the two urban areas, mosquitoes were found to be fully susceptible to chlorpyriphos-methyl 0.4%. {E}levated activity of non-specific esterases and glutathione-{S}-transferases was reported, suggesting multiple resistance mechanisms involved in {A}e. aegypti populations from {B}obo-{D}ioulasso and {O}uagadougou (including cytochrome {P}450). {T}his update to the insecticide resistance status within {A}e. aegypti populations in the two biggest cities is important to better plan dengue vectors control in the country and provides valuable information for improving vector control strategies in {B}urkina {F}aso, {W}est {A}frica.},
  keywords = {{A}edes aegypti ; dengue ; insecticide susceptibility ; metabolic resistance ; {B}urkina {F}aso ; {BURKINA} {FASO} ; {OUAGADOUGOU} ; {BOBO} {DIOULASSO}},
  booktitle = {},
  journal = {{T}ropical {M}edicine and {I}nfectious {D}isease},
  volume = {5},
  numero = {2},
  pages = {84 [9 p.]},
  year = {2020},
  DOI = {10.3390/tropicalmed5020084},
  URL = {https://www.documentation.ird.fr/hor/fdi:010079970},
}