@article{fdi:010079954,
  title = {{H}3.1 eviction marks female germline precursors in {A}rabidopsis},
  author = {{H}ernandez-{L}agana, {E}. and {A}utran, {D}aphn{\'e}},
  editor = {},
  language = {{ENG}},
  abstract = {{I}n flowering plants, germline precursors are differentiated from somatic cells. {T}he female germline precursor of {A}rabidopsis thaliana is located in the internal (nucellar) tissue of the ovule, and is known as the {M}egaspore {M}other {C}ell ({MMC}). {MMC} differentiation in {A}rabidopsis occurs when a cell in the subepidermal layer of the nucellar apex enters the meiotic program. {I}ncreasing evidence has demonstrated that {MMC} specification is a plastic process where the number and developmental outcome of {MMC}s are variable. {D}uring its differentiation, the {MMC} displays specific chromatin hallmarks that distinguish it from other cells within the primordium. {T}o date, these signatures have been only analyzed at developmental stages where the {MMC} is morphologically conspicuous, and their role in reproductive fate acquisition remains to be elucidated. {H}ere, we show that the histone 3 variant {H}3.1 {HISTONE} {THREE} {RELATED} 13 ({HTR}13) can be evicted in multiple subepidermal cells of the nucellus, but that {H}3.1 eviction persists only in the {MMC}. {T}his pattern is established very early in ovule development and is reminiscent of the specific eviction of {H}3.1 that marks cell cycle exit in other somatic cell types, such as the root quiescent center ({QC}) of {A}rabidopsis. {O}ur findings suggest that cell cycle progression in the subepidermal region of the ovule apex is modified very early in development and is associated with plasticity of reproductive fate acquisition.},
  keywords = {cell cycle ; histone {H}3 ; reproductive competence ; plasticity ; ovule ; development ; {A}rabidopsis},
  booktitle = {},
  journal = {{P}lants},
  volume = {9},
  numero = {10},
  pages = {1322 [8]},
  year = {2020},
  DOI = {10.3390/plants9101322},
  URL = {https://www.documentation.ird.fr/hor/fdi:010079954},
}