Arnal Audrey auteur aut IRD Roche Benjamin auteur aut IRD Gouagna Louis-Clément auteur aut IRD Dujon A. auteur aut IRD Ujvari B. auteur aut IRD Corbel Vincent auteur aut IRD Remoué Franck auteur aut IRD Poinsignon Anne auteur aut IRD Pompon Julien auteur aut IRD Giraudeau M. auteur aut IRD Simard Frédéric auteur aut IRD Missé Dorothée auteur aut IRD Lefèvre Thierry auteur aut IRD Thomas F. auteur aut IRD text journalArticle eng text/pdf born digital access Cancer is a major public health issue and represents a significant burden in countries with different levels of economic wealth. In parallel, mosquito-borne infectious diseases represent a growing problem causing significant morbidity and mortality worldwide. Acknowledging that these two concerns are both globally distributed, it is essential to investigate whether they have a reciprocal connection that can fuel their respective burdens. Unfortunately, very few studies have examined the link between these two threats. This review provides an overview of the possible links between mosquitoes, mosquito-borne infectious diseases and cancer. We first focus on the impact of mosquitoes on carcinogenesis in humans including the transmission of oncogenic pathogens through mosquitoes, the immune reactions following mosquito bites, the presence of non-oncogenic mosquito-borne pathogens, and the direct transmission of cancer cells. The second part of this review deals with the direct or indirect consequences of cancer in humans on mosquito behaviour. Thirdly, we discuss the potential impacts that natural cancers in mosquitoes can have on their life history traits and therefore on their vector capacity. Finally, we discuss the most promising research avenues on this topic and the integrative public health strategies that could be envisioned in this context. specialized Public health Integrative strategies Oncogenic pathogens Inflammatory reactions Cancer cells transmission Mosquito life history traits 050 052 743 140631 [6 p.] 2020 0048-9697 https://www.documentation.ird.fr/hor/fdi:010079774 10.1016/j.scitotenv.2020.140631 0048-9697 [F B010079774] https://www.documentation.ird.fr/hor/fdi:010079774 https://www.documentation.ird.fr/intranet/publi/2020/10/010079774.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2020-11-12 2025-02-24 fdi:010079774 fre