@article{fdi:010079771,
  title = {{C}limate and urbanization drive mosquito preference for humans},
  author = {{R}ose, {N}. {H}. and {S}ylla, {M}. and {B}adolo, {A}. and {L}utomiah, {J}. and {A}yala, {D}iego and {A}ribodor, {O}. {B}. and {I}be, {N}. and {A}korli, {J}. and {O}too, {S}. and {M}utebi, {J}. {P}. and {K}riete, {A}. {L}. and {E}wing, {E}. {G}. and {S}ang, {R}. and {G}loria-{S}oria, {A}. and {P}owell, {J}. {R}. and {B}aker, {R}. {E}. and {W}hite, {B}. {J}. and {C}rawford, {J}. {E}. and {M}c{B}ride, {C}. {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he majority of mosquito-borne illness is spread by a few mosquito species that have evolved to specialize in biting humans, yet the precise causes of this behavioral shift are poorly understood. {W}e address this gap in the arboviral vector {A}edes aegypti. {W}e first collect and characterize the behavior of mosquitoes from 27 sites scattered across the species' ancestral range in sub-{S}aharan {A}frica, revealing previously unrecognized variation in preference for human versus animal odor {W}e then use modeling to show that over 80% of this variation can be predicted by two ecological factors-dry season intensity and human population density. {F}inally, we integrate this information with whole-genome sequence data from 375 individual mosquitoes to identify a single underlying ancestry component linked to human preference. {G}enetic changes associated with human specialist ancestry were concentrated in a few chromosomal regions. {O}ur findings suggest that human-biting in this important disease vector originally evolved as a by-product of breeding in human-stored water in areas where doing so provided the only means to survive the long, hot dry season. {O}ur model also predicts that the rapid urbanization currently taking place in {A}frica will drive further mosquito evolution, causing a shift toward human-biting in many large cities by 2050.},
  keywords = {{AFRIQUE} {SUBSAHARIENNE}},
  booktitle = {},
  journal = {{C}urrent {B}iology},
  volume = {30},
  numero = {18},
  pages = {3570--3579 + 6 p.},
  ISSN = {0960-9822},
  year = {2020},
  DOI = {10.1016/j.cub.2020.06.092},
  URL = {https://www.documentation.ird.fr/hor/fdi:010079771},
}