@article{fdi:010079677,
  title = {{G}enetic structure of the mosquito {A}edes aegypti in local forest and domestic habitats in {G}abon and {K}enya},
  author = {{X}ia, {S}. {Y}. and {C}osme, {L}. {V}. and {L}utomiah, {J}. and {S}ang, {R}. and {N}gangue, {M}. {F}. and {R}ahola, {N}il and {A}yala, {D}iego and {P}owell, {J}. {R}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {T}he mosquito {A}edes aegypti is a devastating disease vector transmitting several important human arboviral diseases. {I}n its native range in {A}frica, the mosquito can be found in both the ancestral forest habitat and anthropogenic habitats such as villages. {H}ow do the different habitats impact the population genetic structure of the local mosquito populations? {M}ethods: {T}o address this question, we simultaneously sampled {A}e. aegypti from the forest and local villages in {L}a {L}ope, {G}abon and {R}abai, {K}enya. {T}he mosquitoes were genotyped at 12 microsatellite loci and a panel of similar to 25,000 single nucleotide polymorphisms ({SNP}s), which allowed us to estimate their genetic ancestries and the population genetic structure related to habitats and sampling sites. {R}esults: {I}n the context of the global population genetic structure of {A}e. aegypti, clustering analysis showed that mosquitoes from the same locality ({L}a {L}ope or {R}abai) have similar genetic ancestry, regardless of their habitats. {F}urther analysis at the local scale also found no strong genetic differentiation between the forest and village mosquitoes in both {L}a {L}ope and {R}abai. {I}nterestingly, these results from our 2017 samples from {R}abai, {K}enya contrast to the documentation of genetic differentiation between village and forest mosquito collections from 1975-1976 and 2009. {B}etween-habitat measures of genetic difference ({F}-st) vary across the genome, with a peak of high divergence observed at the third chromosome only in the {L}a {L}ope populations. {C}onclusion: {C}ollectively, these results demonstrated that there is little genetic isolation between forest and village habitats, which suggests possible extensive gene flow between them. {F}rom an epidemiological perspective, the forest habitat could act as a refuge for mosquitoes against vector control programmes in the domestic settings. {M}oreover, sylvatic populations could play a role in zoonotic pathogen transferred to humans. {T}herefore, future studies on disease transmission and vector control planning in the study area should take natural populations into consideration.},
  keywords = {{A}edes aegypti ; {F}orest and domestic habitat ; {D}omestication ; {A}frica ; {P}opulation genetic structure ; {GABON} ; {KENYA} ; {LA} {LOPE} ; {RABAI}},
  booktitle = {},
  journal = {{P}arasites and {V}ectors},
  volume = {13},
  numero = {1},
  pages = {417 [13 ]},
  ISSN = {1756-3305},
  year = {2020},
  DOI = {10.1186/s13071-020-04278-w},
  URL = {https://www.documentation.ird.fr/hor/fdi:010079677},
}