@article{fdi:010079569, title = {{A} second population-based cohort study in {C}ameroon confirms the temporal relationship between onchocerciasis and epilepsy}, author = {{C}hesnais, {C}edric and {B}izet, {C}harlotte and {C}ampillo, {J}. {T}. and {N}jamnshi, {W}. {Y}. and {B}opda, {J}. and {N}wane, {P}. and {P}ion, {S}{\'e}bastien and {N}jamnshi, {A}. {K}. and {B}oussinesq, {M}ichel}, editor = {}, language = {{ENG}}, abstract = {{T}o confirm our earlier evidence of a temporal and dose-response relationship between onchocerciasis and epilepsy, we conducted another cohort study in a different setting in {C}ameroon. {I}ndividuals whose {O}nchocerca volvulus microfilarial density ({O}v-{MFD}) was measured in 1992-1994 when they were children were revisited in 2019 to determine if they acquired epilepsy. {W}ith reference to individuals with no microfilariae in 1992-1994, the relative risks of acquiring epilepsy were 0.96, 2.76, 3.67, and 11.87 in subjects with initial {O}v-{MFD} of 1-7, 8-70, 71-200, and > 200 microfilariae per skin snip, respectively. {T}his study further demonstrates reproducibility using the {B}radford {H}ill's criteria for causality.}, keywords = {onchocerciasis ; epilepsy ; causal relationship ; {A}frica ; cohort ; {CAMEROUN}}, booktitle = {}, journal = {{O}pen {F}orum {I}nfectious {D}iseases}, volume = {7}, numero = {6}, pages = {ofaa206 [5]}, ISSN = {2328-8957}, year = {2020}, DOI = {10.1093/ofid/ofaa206}, URL = {https://www.documentation.ird.fr/hor/fdi:010079569}, }