@article{fdi:010079564,
  title = {{A}edes mosquito salivary components and their effect on the immune response to arboviruses},
  author = {{G}uerrero, {D}. and {C}antaert, {T}. and {M}iss{\'e}, {D}oroth{\'e}e},
  editor = {},
  language = {{ENG}},
  abstract = {{V}ector-borne diseases are responsible for over a billion infections each year and nearly one million deaths. {M}osquito-borne dengue virus, {W}est {N}ile, {J}apanese encephalitis, {Z}ika, {C}hikungunya, and {R}ift {V}alley {F}ever viruses constitute major public health problems in regions with high densities of arthropod vectors. {D}uring the initial step of the transmission cycle, vector, host, and virus converge at the bite site, where local immune cells interact with the vector's saliva. {H}ematophagous mosquito saliva is a mixture of bioactive components known to modulate vertebrate hemostasis, immunity, and inflammation during the insect's feeding process. {T}he capacity of mosquito saliva to modulate the host immune response has been well-studied over the last few decades and has led to the consensus that the presence of saliva is linked to the enhancement of virus transmission, host susceptibility, disease progression, viremia levels, and mortality. {W}e review some of the major aspects of the interactions between mosquito saliva and the host immune response that may be useful for future studies on the control of arboviruses.},
  keywords = {arbovirus ; mosquito saliva ; immune response ; saliva composition ; {A}edes spp},
  booktitle = {},
  journal = {{F}rontiers in {C}ellular and {I}nfection {M}icrobiology},
  volume = {10},
  numero = {},
  pages = {407 [11]},
  ISSN = {2235-2988},
  year = {2020},
  DOI = {10.3389/fcimb.2020.00407},
  URL = {https://www.documentation.ird.fr/hor/fdi:010079564},
}