Elnour M. A. B. auteur aut IRD Moustafa M. A. M. auteur aut IRD Khogali R. auteur aut IRD Azrag R. S. auteur aut IRD Alanazi A. D. auteur aut IRD Kheir A. auteur aut IRD Nakao R. auteur aut IRD De Meeûs Thierry auteur aut IRD Salim B. auteur aut IRD text journalArticle eng text/pdf born digital access Any attempt to control a mosquito-borne disease should primarily focus on controlling its vector. In Sudan, arboviral infections are a major health problem where periodical outbreaks of arboviruses transmitted byAedes aegyptihave been reported. This preliminary study was performed to uncover the population genetic diversity ofAedes aegyptifrom Red Sea State, Sudan, using mtDNA-COIgene. We performed morphological identification, PCR and DNA nucleotide sequencing and analysed the genetic polymorphism, and isolation by distance ofAedes aegyptifrom four sites. Of the 55 samples successfully sequenced, six haplotypes were revealed. Global haplotype network revealed that the predominant haplotype in Sudan (Hap1; 31 sequences = 56.4%), the second most frequent haplotype (Hap2; 13 sequences = 23.6%) and Hap 5 (3.6%) were identical or genetically close to isolates seen in different countries distributed in the United States, South America, Europe, Asia and two African isolates, one from Kenya and the other from Europa Island (Mozambique Channel). Haplotype 4 (3.6%) appeared closely related to mosquitoes sampled from Cameroon, Kenya, Sri Lanka and India and belonged to a lineage that contained isolates from all over the geographical expansion. Haplotype 6 (1.8%) seemed quite distant from any other sequenced mtDNA. To summarize, four haplotypes were found only in Sudan, and one rare haplotype appeared genetically distant from all other haplotypes, suggesting a local origin. Subdivision measures and testing suggested a probable free (or almost free) migration between the different sites sampled. specialized Aedes aegypti genetic diversity mtDNA Sudan SOUDAN 052 020 144 9 817-823 2020 0931-2048 https://www.documentation.ird.fr/hor/fdi:010079523 10.1111/jen.12816 0931-2048 [F B010079523] https://www.documentation.ird.fr/hor/fdi:010079523 https://www.documentation.ird.fr/intranet/publi/2020/09/010079523.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2020-10-09 2021-06-02 fdi:010079523 fre