Laidoudi Y. auteur aut IRD Medkour H. auteur aut IRD Latrofa M. S. auteur aut IRD Davoust B. auteur aut IRD Diatta Georges auteur aut IRD Sokhna Cheikh auteur aut IRD Barciela A. auteur aut IRD Hernandez-Aguilar R. A. auteur aut IRD Raoult D. auteur aut IRD Otranto D. auteur aut IRD Mediannikov Oleg auteur aut IRD text journalArticle eng text/pdf reformatted digital access Abbreviata caucasica (syn.Physaloptera mordens) has been reported in human and various non-human primates including great apes. The identification of this nematode is seldom performed and relies on egg characterization at the coproscopy, in the absence of any molecular tool. Following the recovery of two adult females ofA. caucasicafrom the feces of wild Senegalese chimpanzees, morphometric characteristics were reported and new data on the width of the esophagus (0.268-0.287 mm) and on the cuticle structure (0.70-0.122 mm) were provided. The molecular characterization of a set of mitochondrial (cox1, 16S rRNA, 12S rRNA) and nuclear (18S rRNA and ITS2) partial genes was performed. Our phylogenetic analysis indicates for the first time thatA. caucasicais monophyletic withPhysalopteraspecies. A novel molecular tool was developed for the routine diagnosis ofA. caucasicaand the surveillance of Nematoda infestations. An A. caucasica-specific qPCR targeting the 12S gene was assessed. The assay was able to detect up to 1.13 x 10(-3)eggs/g of fecal matter irrespective of its consistency, with an efficiency of 101.8% and a perfect adjustment (R-2= 0.99). The infection rate byA. caucasicain the chimpanzee fecal samples was 52.08%. Only 6.19% of the environmental samples were positive for nematode DNA and any forA. caucasica. Our findings indicate the need for further studies to clarify the epidemiology, circulation, life cycle, and possible pathological effects of this infestation using the molecular tool herein developed. specialized Abbreviata caucasica Physaloptera mordens Pan troglodytes verus wild chimpanzees nematode zoonosis Senegal SENEGAL 052 080 9 7 517 [22 ] 2020 https://www.documentation.ird.fr/hor/fdi:010079479 10.3390/pathogens9070517 [F B010079479] https://www.documentation.ird.fr/hor/fdi:010079479 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-08/010079479.pdf IRD - Base Horizon / Pleins textes 2020-09-17 2025-02-24 fdi:010079479 fre