%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Fruchard, C.
%A Badouin, H.
%A Latrasse, D.
%A Devani, R. S.
%A Muyle, A.
%A Rhoné, Bénédicte
%A Renner, S. S.
%A Banerjee, A. K.
%A Bendahmane, A.
%A Marais, G. A. B.
%T Evidence for dosage compensation in Coccinia grandis, a plant with a highly heteromorphic XY system
%D 2020
%L fdi:010079466
%G ENG
%J Genes
%K dioecy ; sex chromosomes ; Y degeneration ; sex-biased genes ; cucurbits
%M ISI:000557284900001
%N 7
%P art. 787 [18 ]
%R 10.3390/genes11070787
%U https://www.documentation.ird.fr/hor/fdi:010079466
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-08/010079466.pdf
%V 11
%W Horizon (IRD)
%X About 15,000 angiosperms are dioecious, but the mechanisms of sex determination in plants remain poorly understood. In particular, how Y chromosomes evolve and degenerate, and whether dosage compensation evolves as a response, are matters of debate. Here, we focus on Coccinia grandis, a dioecious cucurbit with the highest level of X/Y heteromorphy recorded so far. We identified sex-linked genes using RNA sequences from a cross and a model-based method termed SEX-DETector. Parents and F1 individuals were genotyped, and the transmission patterns of SNPs were then analyzed. In the >1300 sex-linked genes studied, maximum X-Y divergence was 0.13-0.17, and substantial Y degeneration is implied by an average Y/X expression ratio of 0.63 and an inferred gene loss on the Y of similar to 40%. We also found reduced Y gene expression being compensated by elevated expression of corresponding genes on the X and an excess of sex-biased genes on the sex chromosomes. Molecular evolution of sex-linked genes in C. grandis is thus comparable to that in Silene latifolia, another dioecious plant with a strongly heteromorphic XY system, and cucurbits are the fourth plant family in which dosage compensation is described, suggesting it might be common in plants.
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