@article{fdi:010079466,
  title = {{E}vidence for dosage compensation in {C}occinia grandis, a plant with a highly heteromorphic {XY} system},
  author = {{F}ruchard, {C}. and {B}adouin, {H}. and {L}atrasse, {D}. and {D}evani, {R}. {S}. and {M}uyle, {A}. and {R}hon{\'e}, {B}{\'e}n{\'e}dicte and {R}enner, {S}. {S}. and {B}anerjee, {A}. {K}. and {B}endahmane, {A}. and {M}arais, {G}. {A}. {B}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A}bout 15,000 angiosperms are dioecious, but the mechanisms of sex determination in plants remain poorly understood. {I}n particular, how {Y} chromosomes evolve and degenerate, and whether dosage compensation evolves as a response, are matters of debate. {H}ere, we focus on {C}occinia grandis, a dioecious cucurbit with the highest level of {X}/{Y} heteromorphy recorded so far. {W}e identified sex-linked genes using {RNA} sequences from a cross and a model-based method termed {SEX}-{DET}ector. {P}arents and {F}1 individuals were genotyped, and the transmission patterns of {SNP}s were then analyzed. {I}n the >1300 sex-linked genes studied, maximum {X}-{Y} divergence was 0.13-0.17, and substantial {Y} degeneration is implied by an average {Y}/{X} expression ratio of 0.63 and an inferred gene loss on the {Y} of similar to 40%. {W}e also found reduced {Y} gene expression being compensated by elevated expression of corresponding genes on the {X} and an excess of sex-biased genes on the sex chromosomes. {M}olecular evolution of sex-linked genes in {C}. grandis is thus comparable to that in {S}ilene latifolia, another dioecious plant with a strongly heteromorphic {XY} system, and cucurbits are the fourth plant family in which dosage compensation is described, suggesting it might be common in plants.},
  keywords = {dioecy ; sex chromosomes ; {Y} degeneration ; sex-biased genes ; cucurbits},
  booktitle = {},
  journal = {{G}enes},
  volume = {11},
  numero = {7},
  pages = {art. 787 [18 p.]},
  year = {2020},
  DOI = {10.3390/genes11070787},
  URL = {https://www.documentation.ird.fr/hor/fdi:010079466},
}