@article{fdi:010079341,
  title = {{A}n update on {T}oscana virus distribution, genetics, medical and diagnostic aspects},
  author = {{A}yhan, {N}azli and {C}harrel, {R}. {N}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {T}oscana virus is an arbovirus transmitted by sand flies within the {M}editerranean area where it can cause febrile illness and neuroinvasive infections during the seasonal circulation period of the vector. {A}lthough it is an important cause of meningitis and encephalitis, it remains a neglected virus with limited published data, as demonstrated by <250 peer-reviewed articles since the 1970s. {O}bjective: {T}he last review article on {T}oscana virus was published in 2012. {T}he aim was to compile peer-reviewed articles to provide an updated review highlighting recent findings to complement previous review articles. {S}ources: {P}ub{M}ed database was searched using the '{T}oscana virus' keyword from 2010 to present. {A} total of 152 articles were retrieved and identified studies were assessed for novel information on virus genetics, and geographic and medical aspects compared with existing knowledge reported in previous review articles. {C}ontent: {S}tudies addressing medical, veterinary and entomological aspects have provided evidence that {T}oscana virus is present in {N}orth {A}frica, in the {B}alkan {P}eninsula, and in most of the {M}editerranean islands. {B}esides the two previously recognized genetic lineages, a novel evolutionary lineage has been identified in the {B}alkan {P}eninsula. {C}o-circulation of two genetic lineages has been demonstrated in {F}rance, in {T}urkey and in {C}roatia. {I}n addition to meningitis and meningo-encephalitis, which have been reported for 40 years, various neuroinvasive forms have been recently reported such as {G}uillain-{B}arre syndrome, hydrocephalus, myositis, fasciitis, polymyeloradiculopathy, deafness and facial paralysis.},
  keywords = {{A}rbovirus ; {B}unyavirales ; {E}merging ; {E}ncephalitis ; {E}ndemic ; {M}editerranean ; {M}eningitis ; {P}hlebotomine ; {P}hlebovirus ; {S}and fly ; {BALKANS} ; {AFRIQUE} {DU} {NORD} ; {ITALIE} ; {ESPAGNE} ; {FRANCE} ; {PORTUGAL} ; {TURQUIE} ; {GRECE} ; {CHYPRE} ; {ELBE} ; {MALTE} ; {TUNISIE} ; {CROATIE} ; {CORSE} ; {TUNISIE} ; {ALGERIE} ; {BOSNIE} ; {HERZEGOVINE} ; {KOSOVO} ; {BULGARIE} ; {ZONE} {MEDITERRANEENNE}},
  booktitle = {},
  journal = {{C}linical {M}icrobiology and {I}nfection},
  volume = {26},
  numero = {8},
  pages = {1017--1023},
  ISSN = {1198-743{X}},
  year = {2020},
  DOI = {10.1016/j.cmi.2019.12.015},
  URL = {https://www.documentation.ird.fr/hor/fdi:010079341},
}