@article{fdi:010079262, title = {{N}on-randomized controlled trial of the long-term efficacy of an {E}cohealth intervention against {C}hagas disease in {Y}ucatan, {M}exico}, author = {{W}aleckx, {E}tienne and {P}{\'e}rez-{C}arrillo, {S}. and {C}hávez-{L}azo, {S}. and {P}asos-{A}lquicira, {R}. and {C}ámara-{H}eredia, {M}. and {A}cuña-{L}izama, {J}. and {C}ollí-{B}alám, {F}. and {C}ámara-{M}ejía, {J}. and {R}amírez-{S}ierra, {M}.{J}. and {C}ruz-{C}han, {V}. and {R}osado-{V}allado, {M}. and {V}azquez-{N}arvaez, {S}. and {N}ajera-{V}ázquez, {R}. and {G}ourbi{\`e}re, {S}. and {D}umonteil, {E}.}, editor = {}, language = {{ENG}}, abstract = {{N}on-domiciliated intrusive triatomine vectors are responsible for a low but significant transmission of {T}rypanosoma cruzi to humans. {T}heir control is a challenge as insecticide spraying is of limited usefulness, and alternative strategies need to be developed for a sustainable control. {W}e performed a non-randomized controlled trial of an {E}cohealth intervention based on window insect screens and community participation to reduce house infestation by {T}riatoma dimidiata in two rural villages in {Y}ucatan, {M}exico. {E}fficacy of the intervention was measured over a three years follow-up period and entomological indicators showed that the proportion of triatomines found inside houses was significantly reduced in houses with insect screens, which effectively kept more bugs on the outside of houses. {U}sing a previously developed model linking entomological data to the prevalence of infection in human, we predicted that the intervention would lead to a 32% reduction in yearly incidence and in the prevalence of {T}. cruzi infection. {T}he cost for the coverage of all the windows of a house was of comparable magnitude to what families currently spend on various domestic insecticide, and most screens were still in good conditions after three years. {I}n conclusion, the {E}cohealth approach proposed here is effective for the long-term and sustainable control of intrusive {T}. dimidiata vectors in the {Y}ucatan peninsula, {M}exico. {T}his strategy may also be easily adapted to other intrusive triatomine species as well as other regions/countries with comparable eco-epidemiological settings, and would be an excellent component of a larger integrated program for the control of a variety of other vector-borne diseases, bringing additional benefits to the communities. {O}ur results should encourage a further scaling-up of our implementation strategy in additional villages in the region.}, keywords = {{YUCATAN} ; {MEXIQUE}}, booktitle = {}, journal = {{PL}os {N}eglected {T}ropical {D}iseases}, volume = {12}, numero = {7}, pages = {art. e0006605 [15 ]}, ISSN = {1935-2735}, year = {2018}, DOI = {10.1371/journal.pntd.0006605}, URL = {https://www.documentation.ird.fr/hor/fdi:010079262}, }