@article{fdi:010079117,
  title = {{Y}east-based biosensors : current applications and new developments},
  author = {{M}artin-{Y}ken, {H}{\'e}l{\`e}ne},
  editor = {},
  language = {{ENG}},
  abstract = {{B}iosensors are regarded as a powerful tool to detect and monitor environmental contaminants, toxins, and, more generally, organic or chemical markers of potential threats to human health. {T}hey are basically composed of a sensor part made up of either live cells or biological active molecules coupled to a transducer/reporter technological element. {W}hole-cells biosensors may be based on animal tissues, bacteria, or eukaryotic microorganisms such as yeasts and microalgae. {A}lthough very resistant to adverse environmental conditions, yeasts can sense and respond to a wide variety of stimuli. {A}s eukaryotes, they also constitute excellent cellular models to detect chemicals and organic contaminants that are harmful to animals. {F}or these reasons, combined with their ease of culture and genetic modification, yeasts have been commonly used as biological elements of biosensors since the 1970s. {T}his review aims first at giving a survey on the different types of yeast-based biosensors developed for the environmental and medical domains. {W}e then present the technological developments currently undertaken by academic and corporate scientists to further drive yeasts biosensors into a new era where the biological element is optimized in a tailor-made fashion by in silico design and where the output signals can be recorded or followed on a smartphone.},
  keywords = {yeasts ; biosensors ; cell signaling ; environmental contaminants ; detection},
  booktitle = {},
  journal = {{B}iosensors},
  volume = {10},
  numero = {5},
  pages = {art. 51 [19 p.]},
  year = {2020},
  DOI = {10.3390/bios10050051},
  URL = {https://www.documentation.ird.fr/hor/fdi:010079117},
}