Tintillier F. auteur aut IRD Moriou C. auteur aut IRD Petek Sylvain auteur aut IRD Fauchon M. auteur aut IRD Hellio C. auteur aut IRD Saulnier D. auteur aut IRD Ekins M. auteur aut IRD Hooper J. N. A. auteur aut IRD Al-Mourabit A. auteur aut IRD Debitus Cécile auteur aut IRD text journalArticle eng text/pdf reformatted digital access Four new brominated tyrosine metabolites, aplyzanzines C-F (1-4), were isolated from the French Polynesian sponge Pseudoceratina n. sp., along with the two known 2-aminoimidazolic derivatives, purealidin A (5) and 6, previously isolated, respectively, from the sponges Psammaplysilla purpurea and Verongula sp. Their structures were assigned based on the interpretation of their NMR and HRMS data. The compounds exhibited quorum sensing inhibition (QSi) and antifouling activities against several strains of bacteria and microalgae. To our knowledge, the QSi activity of this type of bromotyrosine metabolite is described here for the first time. specialized sponge Pseudoceratina quorum sensing inhibitory activity antifouling Verongiida bromotyrosine POLYNESIE FRANCAISE 035 020 18 5 art. 272 [17 p.] 2020 https://www.documentation.ird.fr/hor/fdi:010079097 10.3390/md18050272 [F B010079097] https://www.documentation.ird.fr/hor/fdi:010079097 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-07/010079097.pdf IRD - Base Horizon / Pleins textes 2020-07-31 2025-02-24 fdi:010079097 fre