@article{fdi:010078467,
  title = {{N}on-essential trace elements dietary exposure in {F}rench {P}olynesia : intake assessment, nail bio monitoring and thyroid cancer risk},
  author = {{Z}idane, {M}. and {R}en, {Y}. and {X}haard, {C}. and {L}eufroy, {A}. and {C}{\^o}te, {S}. and {D}ewailly, {E}. and {N}o{\¨e}l, {L}. and {G}u{\'e}rin, {T}. and {B}ouisset, {P}. and {B}ernagout, {S}. and {P}aaoafaite, {J}ohn and {I}ltis, {J}acques and {T}aquet, {M}arc and {S}uhas, {E}. and {B}ost-{B}ezeaud, {F}. and {P}etitdidier, {P}. and {R}ubino, {C}. and {G}ardon, {J}acques and {V}athaire, {F}. de},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground : {I}n {F}rench {P}olynesia, thyroid cancer mortality and incidence is reported to be the highest in the
world. {E}xcessive levels of non-essential trace elements (n{ETE}) in the body are associated with several types of cancer.
{O}bjective: {T}he present study aims to provide quantitative information on food contamination by mercury ({H}g), lead
({P}b), arsenic ({A}s) and cadmium ({C}d) in {F}rench {P}olynesia and its potential correlation with measurements performed
in fingernails of {P}olynesians, and then to investigate the potential association between these n{ETE} and different
thyroid cancer risks. {M}ethods: {T}he study population included 229 interviewed cases and 373 interviewed controls {W}e
performed a descriptive analysis of {P}olynesian food and examined the association between thyroid cancer risk and daily
intake levels of n{ETE} and with fingernail n{ETE} levels. 
{R}esults : {H}g contamination was mainly present in sea products, {P}b contamination was present in almost all samples, {C}d was detectable in starchy food and {A}s was detectable in all sea products. {N}o patient exceeded dietary contamination {WHO} limits for {P}b, 2 participants exceeded it for {H}g and 3 individuals (0.5%) for cadmium. {I}n fingernail clippings, the most detectable pollutant was {P}b (553 participants), then {H}g (543 participants) then {C}d (only in 130 participants). {T}hyroid cancer risk was increased more than 4 times by {P}b daily intake in patients with a history of cancer in first-degree relatives than in ones without (p for interaction =0.01), and 2 times more in women with more than 3 pregnancies than in those with none or less (p for interaction =0.005); it
was also increased following {A}s intake by more than 30% in patients with a history of cancer in first-degree relatives
than in ones without (p for interaction =0.05). 
{C}onclusion : {L}ocally produced foods are not a source of n{ETE} exposure in {F}rench {P}olynesia. {D}ieatry n{ETE} exposure and fingernail n{ETE} concentration are not associated to differentiated thyroid cancer risk. {N}o correlation found between n{ETE} dietary exposure and fingernail n{ETE} concentration.},
  keywords = {{POLYNESIE} {FRANCAISE}},
  booktitle = {},
  journal = {{A}sian {P}acific {J}ournal of {C}ancer {P}revention},
  volume = {20},
  numero = {2},
  pages = {art. 82370 [13 ]},
  ISSN = {2476-762{X}},
  year = {2019},
  DOI = {10.31557/{APJCP}.2019.20.2.355},
  URL = {https://www.documentation.ird.fr/hor/fdi:010078467},
}