@article{fdi:010078222, title = {{M}ultihost transmission of {S}chistosoma mansoni in {S}enegal, 2015-2018}, author = {{C}atalano, {S}. and {L}eger, {E}. and {F}all, {C}. {B}. and {B}orlase, {A}. and {D}iop, {S}. {D}. and {B}erger, {D}. and {W}ebster, {B}. {L}. and {F}aye, {B}. and {D}iouf, {N}. {D}. and {R}ollinson, {D}. and {S}ene, {M}. and {B}a, {K}halilou and {W}ebster, {J}. {P}.}, editor = {}, language = {{ENG}}, abstract = {{I}n {W}est {A}frica, {S}chistosoma spp. are capable of infecting multiple definitive hosts, a lifecycle feature that may complicate schistosomiasis control. {W}e characterized the evolutionary relationships among multiple {S}chistosoma mansoni isolates collected from snails (intermediate hosts), humans (definitive hosts), and rodents (definitive hosts) in {S}enegal. {O}n a local scale, diagnosis of {S}. mansoni infection ranged 3.8%-44.8% in school-aged children, 1.7%-52.6% in {M}astomys huberti mice, and 1.8%-7.1% in {B}iomphalaria pfeifferi snails. {O}ur phylogenetic framework confirmed the presence of multiple {S}. mansoni lineages that could infect both humans and rodents; divergence times of these lineages varied (0.13-0.02 million years ago). {W}e propose that extensive movement of persons across {W}est {A}frica might have contributed to the establishment of these various multihost {S}. mansoni clades. {H}igh {S}. mansoni prevalence in rodents at transmission sites frequented by humans further highlights the implications that alternative hosts could have on future public health interventions.}, keywords = {{SENEGAL}}, booktitle = {}, journal = {{E}merging {I}nfectious {D}iseases}, volume = {26}, numero = {6}, pages = {1234--1242}, ISSN = {1080-6040}, year = {2020}, DOI = {10.3201/eid2606.200107}, URL = {https://www.documentation.ird.fr/hor/fdi:010078222}, }