@article{fdi:010078134,
  title = {{M}ycetoma epidemiology, diagnosis management, and outcome in three hospital centres in {S}enegal from 2008 to 2018},
  author = {{S}ow, {D}. and {N}diaye, {M}. and {S}arr, {L}. and {K}ante, {M}. {D}. and {L}y, {F}. and {D}iousse, {P}. and {F}aye, {B}. {T}. and {G}aye, {A}. {M}. and {S}okhna, {C}heikh and {R}anque, {S}. and {F}aye, {B}.},
  editor = {},
  language = {{ENG}},
  abstract = {{M}ycetoma is a neglected tropical disease caused by various actinomycetes or fungi. {T}he disease is characterized by the formation of tumor like-swellings and grains. {S}enegal is an endemic country where mycetoma cases are under-or misdiagnosed due to the lack of capacities and knowledge among health workers and the community; and where the management of eumycetoma, burdened by a high amputation rate, is currently inadequate. {T}his study aimed to update data on the epidemiology of mycetoma cases diagnosed in three hospital centres in {S}enegal over a 10 years-period. {A} total of 193 patients, diagnosed from 2008 to 2018, were included in the study. {T}he most frequent presentation was eumycetoma (47.2%); followed by actinomycetoma (36.8%); it remained undetermined in 16.1% of the patients. {T}he mean age was 38.3 years (68.4% of the patients were between 15 and 45 years-old); the male: female ratio was a 2.94; and most were farmers. {O}ne hundred fifty-six (80.8%) patients had used phytotherapy before attending the hospital. {M}ycetoma was mainly located to the lower limbs (91.2%). {G}rains were observed in 85% of the patients; including white (25.6%) and yellow (4.3%) grains. {T}he etiological diagnosis was complex, resulting in negative direct microscopy, culture and/or histopathology findings, which explains that 16.1% remained uncharacterized. {I}n most of cases, actinomycetoma were treated with a combination of cotrimoxazole, amoxicillin/clavulanic acid, and streptomycin; whereas eumycetoma cases were treated with terbinafine. {T}he surgery was done in 100 (51.8%) of the patients including 9 in actinomycetoma, 78 in eumycetoma and 13 in undetermined form. {T}he high number of uncharacterized mycetoma in this study, the delay in attending a qualified health-care facility, and the lack of available adequate antifungal drug, point out the need to strengthen mycetoma management capacities in {S}enegal.},
  keywords = {{SENEGAL}},
  booktitle = {},
  journal = {{PL}o{S} {O}ne},
  volume = {15},
  numero = {4},
  pages = {art. e0231871 [13 p.]},
  ISSN = {1932-6203},
  year = {2020},
  DOI = {10.1371/journal.pone.0231871},
  URL = {https://www.documentation.ird.fr/hor/fdi:010078134},
}