<?xml version="1.0"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>HIV RNA measurement in dried blood spots of HIV-infected patients in Thailand using Abbott m2000 system</dc:title>
  <dc:creator>Khamduang, W.</dc:creator>
  <dc:creator>Kaewbundit, A.</dc:creator>
  <dc:creator>Duangmano, A.</dc:creator>
  <dc:creator>Hongjaisee, S.</dc:creator>
  <dc:creator>Klinbuayaem, V.</dc:creator>
  <dc:creator>Halue, G.</dc:creator>
  <dc:creator>Chutanunta, A.</dc:creator>
  <dc:creator>Sirirungsi, W.</dc:creator>
  <dc:creator>/Jourdain, Gonzague</dc:creator>
  <dc:creator>/Ngo-Giang-Huong, Nicole</dc:creator>
  <dc:description>World Health Organization recommends using dried blood spots (DBS) for HIV RNA viral load (VL) measurement whenever plasma processing is not convenient or feasible. DBS collected from 80 treatment-naive HIV-infected patients presenting in three hospitals of two different regions of Thailand were shipped to a central laboratory along with corresponding plasma specimens. Viral load was measured in both DBS and plasma using the Abbott m2000 system. HIV RNA levels were strongly correlated (r = 0.94) with a mean of differences of 0.23 log(10) copies/mL. Using the 1,000 copies/mL cut-off, the sensitivity of DBS was 97% (95%CI, 91-100%) and specificity was 75% (95%CI, 19-99%). DBS are useful to scale-up HIV RNA VL testing in settings with limited access to VL testing.</dc:description>
  <dc:date>2020</dc:date>
  <dc:type>text</dc:type>
  <dc:identifier>https://www.documentation.ird.fr/hor/fdi:010078131</dc:identifier>
  <dc:identifier>fdi:010078131</dc:identifier>
  <dc:identifier>Khamduang W., Kaewbundit A., Duangmano A., Hongjaisee S., Klinbuayaem V., Halue G., Chutanunta A., Sirirungsi W., Jourdain Gonzague, Ngo-Giang-Huong Nicole. HIV RNA measurement in dried blood spots of HIV-infected patients in Thailand using Abbott m2000 system. 2020, 15 (1),  art. e0227929 [8 p.]</dc:identifier>
  <dc:language>EN</dc:language>
  <dc:coverage>THAILANDE</dc:coverage>
</oai_dc:dc>
